Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Appanna, D.L.; Grundy, B.J.; Szczepan, E.W.; Viswanatha, T.
    Aerobactin synthesis in a cell-free system of Aerobacter aerogenes 62-1 (1984), Biochim. Biophys. Acta, 801, 437-443.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
6.3.2.38 N-ethylmaleimide
-
 Klebsiella aerogenes
6.3.2.38 p-chloromercuribenzoate
-
 Klebsiella aerogenes
6.3.2.39 N-ethylmaleimide
-
 Klebsiella aerogenes
6.3.2.39 p-chloromercuribenzoate
-
 Klebsiella aerogenes

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
6.3.2.38 Mg2+ dependent on Klebsiella aerogenes
6.3.2.39 Mg2+ dependent on Klebsiella aerogenes

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
6.3.2.38 2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O Klebsiella aerogenes
-
 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.38 2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O Klebsiella aerogenes 62-1
-
 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.39 2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O Klebsiella aerogenes
-
 2 ADP + 2 phosphate + aerobactin
-
 ?
6.3.2.39 2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O Klebsiella aerogenes 62-1
-
 2 ADP + 2 phosphate + aerobactin
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
6.3.2.38 Klebsiella aerogenes
-
-
-
6.3.2.38 Klebsiella aerogenes 62-1
-
-
-
6.3.2.39 Klebsiella aerogenes
-
-
-
6.3.2.39 Klebsiella aerogenes 62-1
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
6.3.2.38 partial Klebsiella aerogenes
6.3.2.39 partial Klebsiella aerogenes

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
6.3.2.38 2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O no activity with beta-gamma-ATP Klebsiella aerogenes 2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.38 2 alpha,beta-methylene-ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O no activity with beta-gamma-ATP Klebsiella aerogenes 62-1 2 alpha,beta-methylene-ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.38 2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
-
 Klebsiella aerogenes 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.38 2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O absolute requirement for ATP in aerobactin production. Other nucleoside triphosphates (UTP, CTP and GTP) are not effective in promoting aerobactin synthesis. Utilization of ATP (decrease in its concentration) is also noted when L-lysine or glycine or L-norleucine is used in the place of N6-acetyl-N6-hydroxylysine Klebsiella aerogenes 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.38 2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O
-
 Klebsiella aerogenes 62-1 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.38 2 ATP + citrate + N6-acetyl-N6-hydroxy-L-lysine + H2O absolute requirement for ATP in aerobactin production. Other nucleoside triphosphates (UTP, CTP and GTP) are not effective in promoting aerobactin synthesis. Utilization of ATP (decrease in its concentration) is also noted when L-lysine or glycine or L-norleucine is used in the place of N6-acetyl-N6-hydroxylysine Klebsiella aerogenes 62-1 2 ADP + 2 phosphate + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine
-
 ?
6.3.2.39 2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O
-
 Klebsiella aerogenes 2 ADP + 2 phosphate + aerobactin
-
 ?
6.3.2.39 2 ATP + N2-citryl-N6-acetyl-N6-hydroxy-L-lysine + N6-acetyl-N6-hydroxy-L-lysine + H2O
-
 Klebsiella aerogenes 62-1 2 ADP + 2 phosphate + aerobactin
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
6.3.2.38 37
-
 assay at Klebsiella aerogenes
6.3.2.39 37
-
 assay at Klebsiella aerogenes