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Literature summary extracted from

  • Saito, T.; Yamane, H.; Sakurai, A.; Murofushi, N.; Takahashi, N.; Kamiya, Y.
    Inhibition of ent-kaurene synthase by quaternary ammonium growth retardants (1996), Biosci. Biotechnol. Biochem., 60, 1040-1042.
No PubMed abstract available

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.5.1.13 expression in Escherichia coli of a recombinant GST fused enzyme Cucurbita maxima

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.2.3.19 additional information wide variety of quaternary ammonium compounds with structural similarities to geranylgeranyl diphosphate tested for inhibition, substances shows significant effects on AB activity, but low effects on B activity Fusarium fujikuroi
5.5.1.13 additional information inhibitory effects on partially purified enzyme of 14 quaternary ammonium iodides at 3 different concentrations are reported Cucurbita maxima

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.2.3.19 ent-copalyl diphosphate Cucurbita maxima involved in biosynthesis of gibberellins ent-kaurene + diphosphate
-
 ?
4.2.3.19 ent-copalyl diphosphate Fusarium fujikuroi involved in biosynthesis of gibberellins ent-kaurene + diphosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.2.3.19 Cucurbita maxima
-
-
-
4.2.3.19 Fusarium fujikuroi
-
-
-
5.5.1.13 Cucurbita maxima
-
 pumpkin
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.2.3.19 ent-copalyl diphosphate
-
 Cucurbita maxima ent-kaurene + diphosphate
-
 ?
4.2.3.19 ent-copalyl diphosphate
-
 Fusarium fujikuroi ent-kaurene + diphosphate
-
 ?
4.2.3.19 ent-copalyl diphosphate involved in biosynthesis of gibberellins Cucurbita maxima ent-kaurene + diphosphate
-
 ?
4.2.3.19 ent-copalyl diphosphate involved in biosynthesis of gibberellins Fusarium fujikuroi ent-kaurene + diphosphate
-
 ?
5.5.1.13 geranylgeranyl diphosphate
-
 Cucurbita maxima copalyl diphosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.2.3.19 additional information part of bifunctional enzyme catalyzing the two step reaction from trans-geranylgeranyl-diphosphate to ent-kaurene, first step is catalyzed by EC 5.5.1.13 (ent-kaurene synthase A) Cucurbita maxima
4.2.3.19 additional information part of bifunctional enzyme catalyzing the two step reaction from trans-geranylgeranyl-diphosphate to ent-kaurene, first step is catalyzed by EC 5.5.1.13 (ent-kaurene synthase A) Fusarium fujikuroi