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Literature summary extracted from

  • Foster, J.L.; Higgins, G.C.; Jackson, F.R.
    Biochemical properties and cellular localization of the Drosophila DG1 cGMP-dependent protein kinase (1996), J. Biol. Chem., 271, 23322-23328.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.11.12 expressed in Sf9 cells Drosophila melanogaster

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.11.12 Mg2+ maximal activation at 40-50 mM Drosophila melanogaster

Organism

EC Number Organism UniProt Comment Textmining
2.7.11.12 Drosophila melanogaster Q03042
-
-

Synonyms

EC Number Synonyms Comment Organism
2.7.11.12 cGMP-dependent protein kinase, isozyme 1
-
 Drosophila melanogaster
2.7.11.12 DG1 protein kinase
-
 Drosophila melanogaster

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.11.12 8-bromo-cAMP 50% activation at 0.00062 mM Drosophila melanogaster
2.7.11.12 8-bromo-cGMP 50% activation at 0.00004 mM Drosophila melanogaster
2.7.11.12 cAMP 50% activation at 0.0117 mM, activation is not cooperative Drosophila melanogaster
2.7.11.12 cGMP cGMP, 0.010 mM, stimulated histone H2B phosphorylation by the DG1 protein kinase 20-fold Drosophila melanogaster
2.7.11.12 cGMP 50% activation at 0.00019 mM, cooperative activation Drosophila melanogaster
2.7.11.12 cIMP 50% activation at 0.0053 mM Drosophila melanogaster