Literature summary extracted from

Pajula, R.L.; Raina, A.
Methylthioadenosine, a potent inhibitor of spermine synthase from bovine brain (1979), FEBS Lett., 99, 343-345.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.5.1.22	5'-methylthioadenosine	partially reversible by adenosine	Bos taurus
2.5.1.22	S-adenosyl-L-homocysteine	not	Bos taurus
2.5.1.22	S-adenosyl-L-methionine	not	Bos taurus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.5.1.22	0.0006	-	S-adenosylmethioninamine	-	Bos taurus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.5.1.22	Bos taurus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.5.1.22	brain	-	Bos taurus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.5.1.22	S-adenosylmethioninamine + spermidine	-	Bos taurus	5'-methylthioadenosine + spermine	-	?

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Release 2023.1 (January 2023)