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Literature summary extracted from

  • Okajima, T.; Nakamura, Y.; Uchikawa, M.; Haslam, D.B.; Numata, S.I.; Furukawa, K.; Urano, T.; Furukawa, K.
    Expression cloning of human globoside synthase cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase (2000), J. Biol. Chem., 275, 40498-40503.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.79 expression in Escherichia coli Homo sapiens
2.4.1.88 Gb4-synthase, expression in 1B9 mouse fibroblast L cells, coexpression of SV 40 large T antigen for extrachromosomal replication of the transfected plasmids Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.79 39511
-
 x * 39511, calculation from nucleotide sequence Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.79 Homo sapiens O75752
-
-
2.4.1.88 Homo sapiens O75752
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.79 additional information the enzyme contains five potential N-linked glycosylation sites Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.79 brain
-
 Homo sapiens
-
2.4.1.79 heart
-
 Homo sapiens
-
2.4.1.79 kidney
-
 Homo sapiens
-
2.4.1.79 lung
-
 Homo sapiens
-
2.4.1.79 placenta
-
 Homo sapiens
-
2.4.1.79 testis
-
 Homo sapiens
-
2.4.1.88 kidney cDNA library Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.79 UDP-N-acetyl-D-galactosamine + D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 Homo sapiens UDP + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 ?
2.4.1.88 UDP-N-acetyl-D-galactosamine + N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide
-
 Homo sapiens UDP + N-acetyl-D-galactosaminyl-1,3-N-acetyl-D-galactosaminyl-1,3-D-galactosyl-1,4-D-galactosyl-1,4-D-glucosylceramide i.e. Forssman antigen ?

Subunits

EC Number Subunits Comment Organism
2.4.1.79 ? x * 39511, calculation from nucleotide sequence Homo sapiens

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.4.1.88 37
-
 assay at Homo sapiens

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.4.1.88 6.5
-
 assay at Homo sapiens