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Literature summary extracted from

  • Sarnesto, A.; Koehlin, T.; Thurin, J.; Blaszczyk-Thurin, M.
    Purification of Hgene-encoded beta-galactoside alpha 1->2 fucosyltransferase from human serum (1990), J. Biol. Chem., 265, 15067-15075.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.69 2-mercaptoethanol 1 mM: 50% loss of activity, 10 mM: 90% inhibition Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4.1.69 1.6
-
Galbeta(1-3)GlcNAcbeta(1-3)Galbeta(1-4)Glc-beta-O-PA8 H-gene encoded enzyme Homo sapiens
2.4.1.69 2.5
-
Galbeta(1-4)GlcNAc-beta-O-2-(2-carbomethoxyethylthio)ethyl H-endoced and Se-encoded enzyme Homo sapiens
2.4.1.69 2.7
-
phenyl-beta-O-galactoside H-gene encoded enzyme Homo sapiens
2.4.1.69 2.9
-
Galbeta(1-4)Glc-beta-O-2-(2-carbomethoxyethylthio)ethyl H-encoded enzyme Homo sapiens
2.4.1.69 3.1
-
Galbeta(1-4)Glc-beta-O-2-(2-carbomethoxyethylthio)ethyl Se-encoded enzyme Homo sapiens
2.4.1.69 8.4
-
phenyl-beta-O-galactoside Se-gene encoded enzyme Homo sapiens

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.4.1.69 50000
-
x * 50000, enzyme from serum, SDS-PAGE under reducing conditions Homo sapiens
2.4.1.69 148000
-
gel filtration Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.69 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.69 glycoprotein
-
Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.69 enzyme from serum Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.69 blood serum from AB and mixed secretor phenotype individuals Homo sapiens
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.4.1.69 additional information
-
-
Homo sapiens

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.69 GDP-beta-L-fucose + Galbeta(1-3)GlcNAcbeta(1-3)Galbeta(1-4)Glc-beta-O-PA8
-
Homo sapiens ?
-
?
2.4.1.69 GDP-L-fucose + beta-D-galactosyl-R
-
Homo sapiens GDP + alpha-L-fucosyl-1,2-beta-D-galactosyl-R
-
?

Subunits

EC Number Subunits Comment Organism
2.4.1.69 ? x * 50000, enzyme from serum, SDS-PAGE under reducing conditions Homo sapiens