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Literature summary extracted from

  • Uchida, Y.; Shimmi, O.; Sudoh, M.; Arisawa, M.; Yamada-Okabe, H.
    Characterization of chitin synthase 2 of Saccharomyces cerevisiae II: Both full size and processed enzymes are active for chitin synthesis (1996), J. Biochem., 119, 659-666.
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.16 since chitin synthase 2 can not expressed in bacterial cells or insect cells in an active form, Saccharomyces cerevisiae is used as the host for overexpression Saccharomyces cerevisiae

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.4.1.16 Nikkomycin nikkomycin Z Saccharomyces cerevisiae
2.4.1.16 nikkomycin Z
-
Saccharomyces cerevisiae

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.4.1.16 Mg2+ significant chitin synthase activity in the presence of Mg2+ or Mn2+, even without trypsin treatment Saccharomyces cerevisiae
2.4.1.16 Mn2+ significant chitin synthase activity in the presence of Mg2+ or Mn2+, even without trypsin treatment Saccharomyces cerevisiae

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.16 Saccharomyces cerevisiae
-
chitin synthetase 2
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.16 proteolytic modification chitin synthase 2 activity is independent of the N-terminal 193 amino acid truncation, because partially purified full length enzyme also exhibits the activity without trypsin treatment in the presence of appropriate cations Saccharomyces cerevisiae

Purification (Commentary)

EC Number Purification (Comment) Organism
2.4.1.16
-
Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.4.1.16 UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n
-
Saccharomyces cerevisiae UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1
-
?

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.4.1.16 0.0068
-
nikkomycin Z
-
Saccharomyces cerevisiae