Literature summary extracted from

Pfefferle, W.; Anke, H.; Bross, M.; Steglich, W.
Inhibition of solubilized chitin synthase by chlorinated aromatic compounds isolated from Mushroom cultures (1990), Agric. Biol. Chem., 54, 1381-1384.

No PubMed abstract available

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.4.1.16	2,2'-methylenebis(3,4,6-trichlorophenol)	0.25 mM, 56% inhibition	Coprinopsis cinerea
2.4.1.16	2,3,5,6-Tetrachloro-4-methoxyphenol	0.25 mM, 48% inhibition	Coprinopsis cinerea
2.4.1.16	3,5-Dichloro-4-methoxybenzaldehyde	0.25 mM, 17% inhibition	Coprinopsis cinerea
2.4.1.16	3,5-Dichloro-4-methoxybenzyl alcohol	0.25 mM, 40% inhibition	Coprinopsis cinerea
2.4.1.16	3,5-Dichlorobenzyl alcohol	0.25 mM, 15% inhibition	Coprinopsis cinerea
2.4.1.16	Hexachlorophene	inhibition can be reversed by lecithin	Coprinopsis cinerea
2.4.1.16	oudemansin B	0.25 mM, 31% inhibition	Coprinopsis cinerea
2.4.1.16	Pentachlorophenol	0.25 mM, 67% inhibition	Coprinopsis cinerea
2.4.1.16	strobilurin A	0.25 mM, 24% inhibition	Coprinopsis cinerea
2.4.1.16	strobilurin B	0.25 mM, 29% inhibition	Coprinopsis cinerea

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.1.16	Coprinopsis cinerea	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.1.16	mycelium	-	Coprinopsis cinerea	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.1.16	UDP-N-acetyl-D-glucosamine + [1,4-(N-acetyl-beta-D-glucosaminyl)]n	-	Coprinopsis cinerea	UDP + [1,4-(N-acetyl-beta-D-glucosaminyl)]n+1	-	?

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.4.1.16	0.0085	-	Hexachlorophene	-	Coprinopsis cinerea

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Release 2023.1 (January 2023)