Literature summary extracted from

Madsen, N.
The inhibition of glycogen phosphorylase by uridine diphosphate glucose (1961), Biochem. Biophys. Res. Commun., 6, 310-313.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.4.1.1	UDP	at high glucose 1-phosphate concentration, glycogen synthesis, not phosphorolysis	Oryctolagus cuniculus
2.4.1.1	UDPglucose	competitive to glucose 1-phosphate, non-competitive to phosphate	Agrobacterium tumefaciens
2.4.1.1	UDPglucose	competitive to glucose 1-phosphate, non-competitive to phosphate	Oryctolagus cuniculus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.4.1.1	additional information	-	additional information	-	Oryctolagus cuniculus
2.4.1.1	1.6	-	glucose 1-phosphate	-	Agrobacterium tumefaciens
2.4.1.1	1.7	-	glucose 1-phosphate	phosphorylase a	Oryctolagus cuniculus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.4.1.1	Agrobacterium tumefaciens	-	-	-
2.4.1.1	Oryctolagus cuniculus	-	-	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.4.1.1	partial	Agrobacterium tumefaciens

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.4.1.1	liver	-	Oryctolagus cuniculus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.4.1.1	glycogen + glucose 1-phosphate	-	Oryctolagus cuniculus	glycogen + phosphate	-	r
2.4.1.1	glycogen + glucose 1-phosphate	-	Agrobacterium tumefaciens	glycogen + phosphate	-	r
2.4.1.1	[(1->4)-alpha-D-glucosyl]n + phosphate	-	Oryctolagus cuniculus	[(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate	-	r
2.4.1.1	[(1->4)-alpha-D-glucosyl]n + phosphate	-	Agrobacterium tumefaciens	[(1->4)-alpha-D-glucosyl]n-1 + alpha-D-glucose 1-phosphate	-	r

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.4.1.1	pyridoxal 5'-phosphate	requirement	Oryctolagus cuniculus
2.4.1.1	pyridoxal 5'-phosphate	requirement	Agrobacterium tumefaciens

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.4.1.1	0.67	-	UDPglucose	-	Agrobacterium tumefaciens
2.4.1.1	0.92	-	UDPglucose	-	Oryctolagus cuniculus

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Release 2023.1 (January 2023)