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Literature summary extracted from

  • Morgunov, I.G.; Sharishev, A.A.; Mikulinskaya, O.V.; Sokolov, D.M.; Finogenova, T.V.
    Isolation, purification and some properties of citrate synthase from citric acid-accumulating yeasts Yarrowia (Candida) lipolytica (1994), Biokhimiya, 59, 1320-1329.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.3.1 ATP noncompetitive against acetyl-CoA Yarrowia lipolytica
2.3.3.1 citrate
-
 Yarrowia lipolytica

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.3.1 0.005
-
 oxaloacetate
-
 Yarrowia lipolytica
2.3.3.1 0.01
-
 acetyl-CoA
-
 Yarrowia lipolytica
2.3.3.1 5
-
 oxaloacetate
-
 Yarrowia lipolytica
2.3.3.1 10
-
 acetyl-CoA
-
 Yarrowia lipolytica

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.3.1 40000
-
 2 * 40000, SDS-PAGE Yarrowia lipolytica
2.3.3.1 70000
-
 gel filtration Yarrowia lipolytica

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.1 Yarrowia lipolytica
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.3.1
-
 Yarrowia lipolytica

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.3.1 161.2
-
-
 Yarrowia lipolytica

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.3.1 acetyl-CoA + oxaloacetate + H2O
-
 Yarrowia lipolytica citrate + CoA
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.3.1 dimer 2 * 40000, SDS-PAGE Yarrowia lipolytica

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.3.1 8.5
-
-
 Yarrowia lipolytica