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Literature summary extracted from

  • Madi, A.; Punyiczki, M.; di Rao, M.; Piacentini, M.; Fesus, L.
    Biochemical characterization and localization of transglutaminase in wild-type and cell-death mutants of the nematode Caenorhabditis elegans (1998), Eur. J. Biochem., 253, 583-590.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 EGTA 2.5 mM, 94% inhibition Caenorhabditis elegans
2.3.2.13 GTP weak inhibition in the millimolar range Caenorhabditis elegans
2.3.2.13 HgCl2 5 mM, 96% inhibition in the presence of 10 mM Ca2+ Caenorhabditis elegans
2.3.2.13 iodoacetamide 10 mM, 62% inhibition in the presence of 10 mM Ca2+ Caenorhabditis elegans
2.3.2.13 MgCl2 5 mM, 88% inhibition, 30% inhibition in the presence of 10 mM Ca2+ Caenorhabditis elegans
2.3.2.13 NH4+ 5 mM, 36% inhibition Caenorhabditis elegans
2.3.2.13 ZnCl2 5 mM, 97.5% inhibition, 43% inhibition in the presence of 10 mM Ca2+ Caenorhabditis elegans

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ maximal activity at 10 mM Caenorhabditis elegans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.13 61000
-
 x * 61000 Da, SDS-PAGE, immunoblot Caenorhabditis elegans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.2.13 protein-bound gamma-glutamine + alkylamine Caenorhabditis elegans transglutaminase is probably involved in cell death program protein N5-alkylglutamine + NH3
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Caenorhabditis elegans
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 N-(5-aminopentyl)biotinamide + N,N'-dimethylcasein
-
 Caenorhabditis elegans ?
-
 ?
2.3.2.13 protein-bound gamma-glutamine + alkylamine
-
 Caenorhabditis elegans protein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 protein-bound gamma-glutamine + alkylamine transglutaminase is probably involved in cell death program Caenorhabditis elegans protein N5-alkylglutamine + NH3
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.2.13 ? x * 61000 Da, SDS-PAGE, immunoblot Caenorhabditis elegans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.2.13 8
-
-
 Caenorhabditis elegans