Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Lee, K.N.; Birckbichler, P.J.; Patterson, M.K.
    GTP hydrolysis by guinea pig liver transglutaminase (1989), Biochem. Biophys. Res. Commun., 162, 1370-1375.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.2.13 GDP inhibits hydrolysis of GTP Cavia porcellus
2.3.2.13 GDP inhibits hydrolysis of GTP Homo sapiens
2.3.2.13 GTP-gamma-S inhibition of GTP-hydrolysis Cavia porcellus
2.3.2.13 GTP-gamma-S inhibition of GTP-hydrolysis Homo sapiens

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.2.13 0.0044
-
 GTP GTPase activity Cavia porcellus

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.2.13 Ca2+ requirement Cavia porcellus
2.3.2.13 Ca2+ requirement Homo sapiens
2.3.2.13 Ca2+ activation of GTPase activity Cavia porcellus
2.3.2.13 Mg2+
-
 Homo sapiens
2.3.2.13 Mg2+ stimulation of GTPase activity, 5 mM Cavia porcellus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.2.13 80000
-
 1 * 80000, SDS-PAGE Cavia porcellus

Organism

EC Number Organism UniProt Comment Textmining
2.3.2.13 Cavia porcellus
-
-
-
2.3.2.13 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.2.13 affinity chromatography on GTP-agarose Cavia porcellus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.2.13 erythrocyte
-
 Cavia porcellus
-
2.3.2.13 erythrocyte
-
 Homo sapiens
-
2.3.2.13 liver
-
 Cavia porcellus
-
2.3.2.13 liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.2.13 GTP + H2O intrinsic GTPase activity Cavia porcellus GDP + phosphate
-
 ?
2.3.2.13 protein-bound gamma-glutamine + alkylamine acyl-transfer reaction Cavia porcellus protein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 protein-bound gamma-glutamine + alkylamine acyl-transfer reaction Homo sapiens protein N5-alkylglutamine + NH3
-
 ?
2.3.2.13 putrescine + casein
-
 Cavia porcellus ?
-
 ?
2.3.2.13 putrescine + casein
-
 Homo sapiens ?
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.2.13 monomer
-
 Homo sapiens
2.3.2.13 monomer 1 * 80000, SDS-PAGE Cavia porcellus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.2.13 37
-
 assay at Cavia porcellus
2.3.2.13 37
-
 assay at Homo sapiens