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Literature summary extracted from

  • Aisien, S.O.; Hellmund, C.; Walter, R.D.
    Characterization of the arylalkylamine N-acetyltransferase in Onchocerca volvulus (1996), Parasitol. Res., 82, 369-371.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.87 p-chloro-mercuribenzoate
-
 Onchocerca volvulus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.87 0.0015
-
 tyramine
-
 Onchocerca volvulus
2.3.1.87 0.002
-
 tryptamine
-
 Onchocerca volvulus
2.3.1.87 0.002
-
 octopamine
-
 Onchocerca volvulus
2.3.1.87 0.009
-
 beta-phenylethylamine
-
 Onchocerca volvulus
2.3.1.87 0.024
-
 5-hydroxytryptamine
-
 Onchocerca volvulus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.87 37000
-
 gel filtration Onchocerca volvulus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.87 Onchocerca volvulus
-
 human filarial parasite
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.87 partial Onchocerca volvulus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.87 acetyl-CoA + 5-hydroxytryptamine
-
 Onchocerca volvulus CoA + N-acetyl-5-hydroxytryptamine
-
 ?
2.3.1.87 acetyl-CoA + beta-phenylethylamine
-
 Onchocerca volvulus CoA + N-(2-phenylethyl)-acetaminde
-
 ?
2.3.1.87 acetyl-CoA + octopamine
-
 Onchocerca volvulus CoA + N-acetyloctopamine
-
 ?
2.3.1.87 acetyl-CoA + tryptamine
-
 Onchocerca volvulus CoA + N-acetyltryptamine
-
 ?
2.3.1.87 acetyl-CoA + tyramine
-
 Onchocerca volvulus CoA + N-acetyltyramine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.87 8.5
-
-
 Onchocerca volvulus