Literature summary extracted from

Shi, Y.; Luo, W.; Tian, W.X.; Zhang, T.; Zhou, H.M.
Inactivation and conformational changes of fatty acid synthase from chicken liver during unfolding by sodium dodecyl sulfate (1998), Int. J. Biochem. Cell Biol., 30, 1319-1330.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.85	sodium dodecylsulfate	causes conformational changes at higher concentrations	Gallus gallus

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
2.3.1.85	0.0043	-	acetyl-CoA	-	Gallus gallus
2.3.1.85	0.005	-	malonyl-CoA	-	Gallus gallus
2.3.1.85	0.00796	-	NADPH	-	Gallus gallus

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.85	Gallus gallus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.85	acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+	-	Gallus gallus	palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O	-	?

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.3.1.85	NADPH	-	Gallus gallus

Ki Value [mM]

EC Number	Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
2.3.1.85	0.14	-	sodium dodecylsulfate	-	Gallus gallus

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Release 2023.1 (January 2023)