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Literature summary extracted from

  • Wong, H.; Mattick, J.S.; Wakil, S.J.
    The architecture of the animal fatty acid synthetase. III. Isolation and characterization of beta-ketoacyl reductase (1983), J. Biol. Chem., 258, 15305-15311.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.85 aryl-acyl-beta-alanyl NADP+ inhibits beta-ketoacyl-reductase Gallus gallus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.85 0.0041
-
 NADPH
-
 Gallus gallus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.85 additional information
-
 molecular weight of fragments after proteolytic cleavage Gallus gallus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.85 Gallus gallus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.85 2 beta-ketoacyl reductase containing fragments after sequential proteolysis Gallus gallus

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.85 acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O structure and regulation Gallus gallus
a

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.85 liver
-
 Gallus gallus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.85 1.2
-
 NADPH Gallus gallus
2.3.1.85 2.6
-
 NADPH Gallus gallus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.85 acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+
-
 Gallus gallus palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.85 25
-
 assay at Gallus gallus

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.85 NADPH requirement, high specificity Gallus gallus