EC Number | Cloned (Comment) | Organism |
---|---|---|
2.3.1.85 | gene sequences | Anser sp. |
2.3.1.86 | transformation technique, plasmid YEpFAS2 transformed to and expressed in Escherichia coli maxi-cells | Saccharomyces cerevisiae |
EC Number | General Stability | Organism |
---|---|---|
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Gallus gallus |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Mus musculus |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Homo sapiens |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Rattus norvegicus |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Bos taurus |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Oryctolagus cuniculus |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Canis lupus familiaris |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Anser sp. |
2.3.1.85 | dissociation of native enzyme leads to loss of activity | Columba sp. |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Anser sp. | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Bos taurus | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Canis lupus familiaris | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Columba sp. | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Gallus gallus | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Homo sapiens | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Mus musculus | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Oryctolagus cuniculus | |
2.3.1.85 | 1,3-Dibromo-2-propanone | - |
Rattus norvegicus | |
2.3.1.85 | 2,3-Butanedione | - |
Anser sp. | |
2.3.1.85 | diisopropylfluorophosphate | - |
Anser sp. | |
2.3.1.85 | diisopropylfluorophosphate | - |
Bos taurus | |
2.3.1.85 | diisopropylfluorophosphate | - |
Canis lupus familiaris | |
2.3.1.85 | diisopropylfluorophosphate | - |
Columba sp. | |
2.3.1.85 | diisopropylfluorophosphate | - |
Gallus gallus | |
2.3.1.85 | diisopropylfluorophosphate | - |
Homo sapiens | |
2.3.1.85 | diisopropylfluorophosphate | - |
Mus musculus | |
2.3.1.85 | diisopropylfluorophosphate | - |
Oryctolagus cuniculus | |
2.3.1.85 | diisopropylfluorophosphate | - |
Rattus norvegicus | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Anser sp. | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Bos taurus | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Canis lupus familiaris | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Columba sp. | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Gallus gallus | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Homo sapiens | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Mus musculus | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Oryctolagus cuniculus | |
2.3.1.85 | iodoacetamide | beta-ketoacyl synthetase activity, acetyl-CoA but not malonyl-CoA protects | Rattus norvegicus | |
2.3.1.85 | Phenylglyoxal | - |
Anser sp. | |
2.3.1.85 | PMSF | - |
Anser sp. | |
2.3.1.85 | PMSF | - |
Bos taurus | |
2.3.1.85 | PMSF | - |
Canis lupus familiaris | |
2.3.1.85 | PMSF | - |
Columba sp. | |
2.3.1.85 | PMSF | - |
Gallus gallus | |
2.3.1.85 | PMSF | - |
Homo sapiens | |
2.3.1.85 | PMSF | - |
Mus musculus | |
2.3.1.85 | PMSF | - |
Oryctolagus cuniculus | |
2.3.1.85 | PMSF | - |
Rattus norvegicus | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Anser sp. | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Bos taurus | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Canis lupus familiaris | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Columba sp. | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Gallus gallus | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Homo sapiens | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Mus musculus | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Oryctolagus cuniculus | |
2.3.1.85 | pyridoxal 5'-phosphate | enoyl reductase activity, NADPH protects | Rattus norvegicus | |
2.3.1.86 | 1,3-Dibromo-2-propanone | - |
Saccharomyces cerevisiae |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.86 | additional information | - |
- |
Mycolicibacterium smegmatis |
2.3.1.86 | additional information | - |
alpha6beta6-complex of multifunctional subunits | Saccharomyces cerevisiae |
2.3.1.86 | additional information | - |
amino acid sequence of acyl-carrier-protein | Saccharomyces cerevisiae |
2.3.1.86 | 180000 | - |
alpha6,beta6, 6 * 185000 + 6 * 180000, SDS-PAGE | Saccharomyces cerevisiae |
2.3.1.86 | 185000 | - |
alpha6,beta6, 6 * 185000 + 6 * 180000, SDS-PAGE | Saccharomyces cerevisiae |
2.3.1.86 | 203000 | - |
alpha6,beta6, 6 * 213000 + 6 * 203000, Tris-glycine-SDS-PAGE | Saccharomyces cerevisiae |
2.3.1.86 | 213000 | - |
alpha6,beta6, 6 * 213000 + 6 * 203000, Tris-glycine-SDS-PAGE | Saccharomyces cerevisiae |
2.3.1.86 | 2400000 | - |
sedimentation velocity | Saccharomyces cerevisiae |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Gallus gallus | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Mus musculus | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Homo sapiens | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Rattus norvegicus | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Bos taurus | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Oryctolagus cuniculus | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Canis lupus familiaris | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Anser sp. | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | Columba sp. | multifunctional enzyme, involved in animal fat synthesis | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.86 | acetyl-CoA + malonyl-CoA + NADH + NADPH | Saccharomyces cerevisiae | multifunctional enzyme involved in yeast fat metabolism | ? | - |
? | |
2.3.1.86 | acetyl-CoA + malonyl-CoA + NADH + NADPH | Mycolicibacterium smegmatis | multifunctional enzyme involved in yeast fat metabolism | ? | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.85 | Anser sp. | - |
goose | - |
2.3.1.85 | Bos taurus | - |
- |
- |
2.3.1.85 | Canis lupus familiaris | - |
- |
- |
2.3.1.85 | Columba sp. | - |
pigeon | - |
2.3.1.85 | Gallus gallus | - |
- |
- |
2.3.1.85 | Homo sapiens | - |
- |
- |
2.3.1.85 | Mus musculus | - |
- |
- |
2.3.1.85 | Oryctolagus cuniculus | - |
- |
- |
2.3.1.85 | Rattus norvegicus | - |
- |
- |
2.3.1.86 | Mycolicibacterium smegmatis | - |
- |
- |
2.3.1.86 | Saccharomyces cerevisiae | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.86 | isolation of alpha- and beta-subunits | Saccharomyces cerevisiae |
2.3.1.86 | isolation of alpha- and beta-subunits by citraconic and dimethylmaleic anhydride modification | Saccharomyces cerevisiae |
EC Number | Reaction | Comment | Organism | Reaction ID |
---|---|---|---|---|
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Gallus gallus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Mus musculus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Homo sapiens | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Rattus norvegicus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Bos taurus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Oryctolagus cuniculus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Canis lupus familiaris | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Anser sp. | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | reaction mechanism | Columba sp. | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Gallus gallus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Mus musculus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Homo sapiens | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Rattus norvegicus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Bos taurus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Oryctolagus cuniculus | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Canis lupus familiaris | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Anser sp. | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | structure and regulation | Columba sp. | |
2.3.1.86 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoyl-CoA + 7 CoA + 7 CO2 + 14 NADP+ + 7 H2O | reaction mechanism | Saccharomyces cerevisiae | |
2.3.1.86 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoyl-CoA + 7 CoA + 7 CO2 + 14 NADP+ + 7 H2O | reaction mechanism | Mycolicibacterium smegmatis | |
2.3.1.86 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoyl-CoA + 7 CoA + 7 CO2 + 14 NADP+ + 7 H2O | structure | Saccharomyces cerevisiae | |
2.3.1.86 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ = hexadecanoyl-CoA + 7 CoA + 7 CO2 + 14 NADP+ + 7 H2O | structure and regulation | Saccharomyces cerevisiae |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.85 | adipose tissue | - |
Mus musculus | - |
2.3.1.85 | adipose tissue | - |
Rattus norvegicus | - |
2.3.1.85 | liver | - |
Gallus gallus | - |
2.3.1.85 | liver | - |
Mus musculus | - |
2.3.1.85 | liver | - |
Homo sapiens | - |
2.3.1.85 | liver | - |
Rattus norvegicus | - |
2.3.1.85 | liver | - |
Bos taurus | - |
2.3.1.85 | liver | - |
Oryctolagus cuniculus | - |
2.3.1.85 | liver | - |
Canis lupus familiaris | - |
2.3.1.85 | liver | - |
Anser sp. | - |
2.3.1.85 | liver | - |
Columba sp. | - |
2.3.1.85 | mammary gland | - |
Rattus norvegicus | - |
2.3.1.85 | mammary gland | lactating | Oryctolagus cuniculus | - |
2.3.1.85 | uropygial gland | - |
Anser sp. | - |
EC Number | Storage Stability | Organism |
---|---|---|
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Gallus gallus |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Mus musculus |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Homo sapiens |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Rattus norvegicus |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Bos taurus |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Oryctolagus cuniculus |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Canis lupus familiaris |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Anser sp. |
2.3.1.85 | 0°C, inactivation after 12 h, reactivation after 2 h at 25°C in the presence of NADPH, not acetyl-CoA or NADH | Columba sp. |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Rattus norvegicus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | lactating mammary gland thioesterase II of fatty acid synthetase: products are medium chain fatty acids from C8 to C12 | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Oryctolagus cuniculus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | lactating mammary gland thioesterase II of fatty acid synthetase: products are medium chain fatty acids from C8 to C12 | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Gallus gallus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Mus musculus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Homo sapiens | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Rattus norvegicus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Bos taurus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Oryctolagus cuniculus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Canis lupus familiaris | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Anser sp. | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Columba sp. | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | C20 and C22 fatty acids in the absence of thioesterase activity | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Anser sp. | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | methylmalonyl-CoA instead of malonyl-CoA yields branched fatty acid, e.g. 2,4,6,8-tetramethyldecanoic acid | ? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Gallus gallus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Mus musculus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Homo sapiens | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Rattus norvegicus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Bos taurus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Oryctolagus cuniculus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Canis lupus familiaris | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Anser sp. | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.85 | acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | multifunctional enzyme, involved in animal fat synthesis | Columba sp. | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? | |
2.3.1.86 | acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+ | - |
Mycolicibacterium smegmatis | palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O | - |
? | |
2.3.1.86 | acetyl-CoA + 7 malonyl-CoA + 7 NADH + 7 NADPH + 14 H+ | stable multifunctional enzyme complex: carries acetyl-CoA and malonyl-CoA transacylase, beta-ketoacyl reductase, beta-hydroxyacyl dehydrase activities on beta-subunits and condensing enzyme, i.e. beta-ketoacyl synthetase, enoylacyl reductase activities and acyl-carrier-protein components on alpha-subunits | Saccharomyces cerevisiae | palmitoyl-CoA + 7 CoA + 7 CO2 + 7 NAD+ + 7 NADP+ + 7 H2O | - |
? | |
2.3.1.86 | acetyl-CoA + malonyl-CoA + NADH + NADPH | multifunctional enzyme involved in yeast fat metabolism | Saccharomyces cerevisiae | ? | - |
? | |
2.3.1.86 | acetyl-CoA + malonyl-CoA + NADH + NADPH | multifunctional enzyme involved in yeast fat metabolism | Mycolicibacterium smegmatis | ? | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
2.3.1.85 | More | - |
Mus musculus |
2.3.1.85 | More | - |
Homo sapiens |
2.3.1.85 | More | - |
Bos taurus |
2.3.1.85 | More | - |
Canis lupus familiaris |
2.3.1.85 | More | - |
Anser sp. |
2.3.1.85 | More | - |
Columba sp. |
2.3.1.85 | More | alpha2-dimer of multifunctional subunits: each subunit contains up to seven active centres required for palmitate synthesis | Oryctolagus cuniculus |
2.3.1.85 | More | alpha2-dimer of multifunctional subunits: each subunit contains up to seven active centres required for palmitate synthesis and an acyl carrier site, arranged in three domains but dimer is the only catalytically active form of fatty acid synthase | Rattus norvegicus |
2.3.1.85 | More | condensing enzyme activity requires both subunits | Gallus gallus |
2.3.1.86 | dodecamer | alpha6,beta6, 6 * 185000 + 6 * 180000, SDS-PAGE | Saccharomyces cerevisiae |
2.3.1.86 | dodecamer | alpha6,beta6, 6 * 213000 + 6 * 203000, Tris-glycine-SDS-PAGE | Saccharomyces cerevisiae |
2.3.1.86 | More | - |
Saccharomyces cerevisiae |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Gallus gallus | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Mus musculus | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Homo sapiens | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Rattus norvegicus | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Bos taurus | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Oryctolagus cuniculus | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Canis lupus familiaris | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Anser sp. | |
2.3.1.85 | 4'-phosphopantetheine | requirement, 1 mol associated with 1 mol subunit | Columba sp. | |
2.3.1.85 | additional information | no requirement for FMN | Gallus gallus | |
2.3.1.85 | additional information | no requirement for FMN | Mus musculus | |
2.3.1.85 | additional information | no requirement for FMN | Homo sapiens | |
2.3.1.85 | additional information | no requirement for FMN | Rattus norvegicus | |
2.3.1.85 | additional information | no requirement for FMN | Bos taurus | |
2.3.1.85 | additional information | no requirement for FMN | Oryctolagus cuniculus | |
2.3.1.85 | additional information | no requirement for FMN | Canis lupus familiaris | |
2.3.1.85 | additional information | no requirement for FMN | Anser sp. | |
2.3.1.85 | additional information | no requirement for FMN | Columba sp. | |
2.3.1.85 | NADPH | requirement, high specificity | Gallus gallus | |
2.3.1.85 | NADPH | requirement, high specificity | Mus musculus | |
2.3.1.85 | NADPH | requirement, high specificity | Homo sapiens | |
2.3.1.85 | NADPH | requirement, high specificity | Rattus norvegicus | |
2.3.1.85 | NADPH | requirement, high specificity | Bos taurus | |
2.3.1.85 | NADPH | requirement, high specificity | Oryctolagus cuniculus | |
2.3.1.85 | NADPH | requirement, high specificity | Canis lupus familiaris | |
2.3.1.85 | NADPH | requirement, high specificity | Anser sp. | |
2.3.1.85 | NADPH | requirement, high specificity | Columba sp. | |
2.3.1.86 | 4'-phosphopantetheine | 4.0-5.0 mol per mol enzyme or about 1 mol per 2 subunits | Saccharomyces cerevisiae | |
2.3.1.86 | 4'-phosphopantetheine | 4.0-5.0 mol per mol enzyme | Saccharomyces cerevisiae | |
2.3.1.86 | 4'-phosphopantetheine | alpha-subunit bears prosthetic group | Saccharomyces cerevisiae | |
2.3.1.86 | FMN | requirement, enoyl reductase activity, associated with beta-subunit, 6 mol per mol synthetase | Saccharomyces cerevisiae | |
2.3.1.86 | NADPH | requirement | Saccharomyces cerevisiae | |
2.3.1.86 | NADPH | requirement | Mycolicibacterium smegmatis |