EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.192 | KCl | 80 mM KC1, ca. 30% inhibition, inhibition is seen at all concentrations of glutamine up to 150 mM | Homo sapiens | |
2.3.1.192 | additional information | human enzyme is insensitive to salts | Homo sapiens |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.192 | 120 | - |
L-glutamine | pH 8.0, 30°C | Homo sapiens |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.71 | mitochondrion | - |
Homo sapiens | 5739 | - |
2.3.1.192 | mitochondrion | - |
Homo sapiens | 5739 | - |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.71 | 30500 | - |
gel filtration | Homo sapiens |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.71 | Homo sapiens | - |
- |
- |
2.3.1.192 | Homo sapiens | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.71 | partial | Homo sapiens |
2.3.1.192 | partial | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.71 | liver | - |
Homo sapiens | - |
2.3.1.192 | liver | - |
Homo sapiens | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.71 | benzoyl-CoA + glycine | - |
Homo sapiens | CoA + N-benzoylglycine | - |
? | |
2.3.1.71 | heptanoyl-CoA + glycine | 9.5% of the activity with benzoyl-CoA | Homo sapiens | CoA + N-heptanoylglycine | - |
? | |
2.3.1.71 | indoleacetyl-CoA + glycine | - |
Homo sapiens | CoA + N-indoleacetylglycine | - |
? | |
2.3.1.71 | isovaleryl-CoA + glycine | 9.1% of the activity with benzoyl-CoA | Homo sapiens | CoA + N-isovalerylglycine | - |
? | |
2.3.1.71 | n-butyryl-CoA + glycine | 28% of the activity with benzoyl-CoA | Homo sapiens | CoA + N-butyrylglycine | - |
? | |
2.3.1.71 | salicyl-CoA + glycine | 22% of the activity with benzoyl-CoA | Homo sapiens | CoA + salicyluric acid | - |
? | |
2.3.1.192 | 1-naphtylacetyl-CoA + L-glutamine | 3-5% of the rate with phenacetyl-CoA | Homo sapiens | ? + CoA | - |
? | |
2.3.1.192 | indoleacetyl-CoA + L-glutamine | 3-5% of the rate with phenacetyl-CoA | Homo sapiens | ? + CoA | - |
? | |
2.3.1.192 | additional information | glycination of phenylacetyl-CoA by human phenacetyltransferase can only be detected at a concentration of glycine above 50 mM, and the rates are below 2% of the rate of glutamination | Homo sapiens | ? | - |
? | |
2.3.1.192 | phenylacetyl-CoA + L-glutamine | may substitue for glycine, but at lower rate | Homo sapiens | phenylacetyl-L-glutamine + CoA | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
2.3.1.192 | AAC | - |
Homo sapiens |