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Literature summary extracted from

  • Kelley, M.; Vessey, D.A.
    Isolation and characterization of mitochondrial acyl-CoA: glycine N-acyltransferases from kidney (1993), J. Biochem. Toxicol., 8, 63-69.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.71 hippuric acid
-
Bos taurus
2.3.1.71 K+ 100 mM, 50% inhibition Bos taurus
2.3.1.71 p-hydroxymercuribenzoate 1 mM, 24°C, 90% inhibition after 40 min Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.71 6
-
Gly reaction with benzoyl-CoA Bos taurus
2.3.1.71 7.6
-
salicyl-CoA reaction with salicylyl-CoA Bos taurus
2.3.1.71 79
-
glycine reaction with butyryl-CoA Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.71 mitochondrion
-
Bos taurus 5739
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.71 33500
-
gel filtration Bos taurus
2.3.1.71 34000
-
1 * 34000, SDS-PAGE Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.71 Bos taurus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.71 kidney
-
Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.71 benzoyl-CoA + glycine
-
Bos taurus CoA + N-benzoylglycine
-
?
2.3.1.71 heptanoyl-CoA + glycine 3.9% of the activity with benzoyl-CoA Bos taurus CoA + N-heptanoylglycine
-
?
2.3.1.71 isovaleryl-CoA + glycine 8.4% of the activity with benzoyl-CoA Bos taurus CoA + N-isovalerylglycine
-
?
2.3.1.71 n-butyryl-CoA + glycine 19% of the activity with benzoyl-CoA Bos taurus CoA + N-butyrylglycine
-
?
2.3.1.71 naphthylacetyl-CoA + glycine
-
Bos taurus CoA + N-naphthylacetylglycine
-
?
2.3.1.71 phenylacetyl-CoA + glycine
-
Bos taurus CoA + N-phenylacetylglycine
-
?
2.3.1.71 salicyl-CoA + glycine 15% of the activity with benzoyl-CoA Bos taurus CoA + salicyluric acid
-
?

Subunits

EC Number Subunits Comment Organism
2.3.1.71 monomer 1 * 34000, SDS-PAGE Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.71 0.075
-
hippuric acid
-
Bos taurus