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Literature summary extracted from

  • Alhomida, A.S.
    Inhibition studies of the carnitine acetyltransferase from skeletal muscle of the camel (Camelus dromedarius) by sulfhydryl reagents and metal ions (1996), Biochem. Mol. Biol. Int., 39, 923-931.
    View publication on PubMed

Application

EC Number Application Comment Organism
2.3.1.7 medicine CAT is clinically used in evaluating L-CA and its esters in body fluids and tissues Homo sapiens

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.7 5,5'-dithio-bis(2-nitrobenzoic acid)
-
 Camelus dromedarius
2.3.1.7 5,5'-dithio-bis(2-nitrobenzoic acid)
-
 Mus musculus
2.3.1.7 5,5'-dithio-bis(2-nitrobenzoic acid)
-
 Rattus norvegicus
2.3.1.7 bromoacetylcarnitine
-
 Columba sp.
2.3.1.7 bromoacetylcarnitine
-
 Rattus norvegicus
2.3.1.7 Ca2+
-
 Homo sapiens
2.3.1.7 Ca2+
-
 Saccharomyces cerevisiae
2.3.1.7 Cu2+
-
 Camelus dromedarius
2.3.1.7 CuSO4
-
 Camelus dromedarius
2.3.1.7 Hg2+
-
 Camelus dromedarius
2.3.1.7 HgCl2
-
 Camelus dromedarius
2.3.1.7 iodoacetamide
-
 Camelus dromedarius
2.3.1.7 iodoacetamide
-
 Rattus norvegicus
2.3.1.7 iodoacetic acid
-
 Rattus norvegicus
2.3.1.7 Methoxycarbonyl-CoA disulfide
-
 Camelus dromedarius
2.3.1.7 Mg2+
-
 Saccharomyces cerevisiae
2.3.1.7 Zn2+
-
 Camelus dromedarius
2.3.1.7 Zn2+
-
 Mus musculus
2.3.1.7 ZnSO4
-
 Camelus dromedarius

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.7 microsome
-
 Mus musculus
-
-
2.3.1.7 microsome
-
 Rattus norvegicus
-
-
2.3.1.7 microsome
-
 Camelus dromedarius
-
-
2.3.1.7 microsome
-
 Columba sp.
-
-
2.3.1.7 mitochondrion
-
 Mus musculus 5739
-
2.3.1.7 mitochondrion
-
 Saccharomyces cerevisiae 5739
-
2.3.1.7 mitochondrion membrane-bound Homo sapiens 5739
-
2.3.1.7 mitochondrion membrane-bound Rattus norvegicus 5739
-
2.3.1.7 mitochondrion membrane-bound Camelus dromedarius 5739
-
2.3.1.7 mitochondrion membrane-bound Columba sp. 5739
-
2.3.1.7 peroxisome
-
 Mus musculus 5777
-
2.3.1.7 peroxisome
-
 Homo sapiens 5777
-
2.3.1.7 peroxisome
-
 Rattus norvegicus 5777
-
2.3.1.7 peroxisome
-
 Camelus dromedarius 5777
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.7 acetyl-CoA + carnitine Mus musculus
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Homo sapiens
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Rattus norvegicus
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Saccharomyces cerevisiae
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Camelus dromedarius
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine Columba sp.
-
 O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Mus musculus
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Homo sapiens
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Rattus norvegicus
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Saccharomyces cerevisiae
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Camelus dromedarius
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine Columba sp.
-
 acylcarnitine + CoASH
-
 r
2.3.1.7 acylcarnitine + CoASH Mus musculus
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Homo sapiens
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Rattus norvegicus
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Saccharomyces cerevisiae
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Camelus dromedarius
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH Columba sp.
-
 acyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Mus musculus
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Homo sapiens
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Rattus norvegicus
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Saccharomyces cerevisiae
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Camelus dromedarius
-
 acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH Columba sp.
-
 acetyl-CoA + carnitine
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.7 Camelus dromedarius
-
 arabian camel
-
2.3.1.7 Columba sp.
-
-
-
2.3.1.7 Homo sapiens
-
 human
-
2.3.1.7 Mus musculus
-
 mouse
-
2.3.1.7 Rattus norvegicus
-
 rat
-
2.3.1.7 Saccharomyces cerevisiae
-
 baker's yeast
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.7
-
 Mus musculus
2.3.1.7
-
 Homo sapiens
2.3.1.7
-
 Rattus norvegicus
2.3.1.7
-
 Saccharomyces cerevisiae
2.3.1.7
-
 Camelus dromedarius
2.3.1.7
-
 Columba sp.

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.7 heart
-
 Mus musculus
-
2.3.1.7 heart
-
 Homo sapiens
-
2.3.1.7 heart
-
 Rattus norvegicus
-
2.3.1.7 heart
-
 Columba sp.
-
2.3.1.7 liver
-
 Mus musculus
-
2.3.1.7 liver
-
 Homo sapiens
-
2.3.1.7 liver
-
 Rattus norvegicus
-
2.3.1.7 liver
-
 Columba sp.
-
2.3.1.7 muscle
-
 Rattus norvegicus
-
2.3.1.7 muscle
-
 Camelus dromedarius
-
2.3.1.7 muscle
-
 Columba sp.
-
2.3.1.7 retina
-
 Rattus norvegicus
-
2.3.1.7 skeletal muscle
-
 Rattus norvegicus
-
2.3.1.7 skeletal muscle
-
 Camelus dromedarius
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.7 acetyl-CoA + carnitine
-
 Mus musculus O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Homo sapiens O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Rattus norvegicus O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Saccharomyces cerevisiae O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Camelus dromedarius O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Mus musculus O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Homo sapiens O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Rattus norvegicus O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Saccharomyces cerevisiae O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Camelus dromedarius O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acetyl-CoA + L-(-)carnitine
-
 Columba sp. O-acetylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Mus musculus acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Homo sapiens acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Rattus norvegicus acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Saccharomyces cerevisiae acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Camelus dromedarius acylcarnitine + CoASH
-
 r
2.3.1.7 acyl-CoA + carnitine
-
 Columba sp. acylcarnitine + CoASH
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Mus musculus acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Homo sapiens acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Rattus norvegicus acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Saccharomyces cerevisiae acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Camelus dromedarius acyl-CoA + carnitine
-
 r
2.3.1.7 acylcarnitine + CoASH
-
 Columba sp. acyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Mus musculus acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Homo sapiens acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Rattus norvegicus acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Saccharomyces cerevisiae acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Camelus dromedarius acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + L-(-)carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Mus musculus acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Homo sapiens acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Rattus norvegicus acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Saccharomyces cerevisiae acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Camelus dromedarius acetyl-CoA + carnitine
-
 r
2.3.1.7 O-acetylcarnitine + CoASH
-
 Columba sp. acetyl-CoA + carnitine
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.3.1.7 CAT
-
 Mus musculus
2.3.1.7 CAT
-
 Homo sapiens
2.3.1.7 CAT
-
 Rattus norvegicus
2.3.1.7 CAT
-
 Camelus dromedarius
2.3.1.7 CAT
-
 Columba sp.