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Literature summary extracted from

  • Haubrich, D.R.
    Choline acetyltransferase and its inhibitors (1976), Biol. of Cholinergic Funct. (Goldberg, A. M. , Hanin, I. , eds. ), 1976, 239-266.
No PubMed abstract available

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.6 3-Chloro-4-stilbazole
-
 Bos taurus
2.3.1.6 3-Chloro-4-stilbazole
-
 Cavia porcellus
2.3.1.6 3-Chloro-4-stilbazole
-
 Columba livia
2.3.1.6 3-Chloro-4-stilbazole
-
 Homo sapiens
2.3.1.6 3-Chloro-4-stilbazole
-
 Musa domestica
2.3.1.6 3-Chloro-4-stilbazole
-
 Oryctolagus cuniculus
2.3.1.6 3-Chloro-4-stilbazole
-
 Rattus norvegicus
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Bos taurus
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Cavia porcellus
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Columba livia
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Homo sapiens
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Musa domestica
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Oryctolagus cuniculus
2.3.1.6 4-(1-Naphthylvinyl)pyridine
-
 Rattus norvegicus
2.3.1.6 bromoacetylcholine
-
 Bos taurus
2.3.1.6 bromoacetylcholine
-
 Homo sapiens
2.3.1.6 bromoacetylcholine
-
 Rattus norvegicus
2.3.1.6 coenzyme A
-
 Bos taurus
2.3.1.6 coenzyme A
-
 Rattus norvegicus
2.3.1.6 juglone
-
 Oryctolagus cuniculus
2.3.1.6 additional information
-
 Bos taurus
2.3.1.6 additional information
-
 Cavia porcellus
2.3.1.6 additional information
-
 Columba livia
2.3.1.6 additional information
-
 Homo sapiens
2.3.1.6 additional information
-
 Musa domestica
2.3.1.6 additional information
-
 Oryctolagus cuniculus
2.3.1.6 additional information
-
 Rattus norvegicus
2.3.1.6 N-Methyl-4-(1-naphthylvinyl)pyridine
-
 Bos taurus
2.3.1.6 N-Methyl-4-(1-naphthylvinyl)pyridine
-
 Homo sapiens
2.3.1.6 N-Methyl-4-(1-naphthylvinyl)pyridine
-
 Musa domestica
2.3.1.6 N-Methyl-4-(1-naphthylvinyl)pyridine
-
 Rattus norvegicus
2.3.1.6 Styrylpyridinium salts
-
 Bos taurus
2.3.1.6 Styrylpyridinium salts
-
 Homo sapiens
2.3.1.6 Styrylpyridinium salts
-
 Musa domestica
2.3.1.6 Styrylpyridinium salts
-
 Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.6 additional information
-
 additional information overview Cavia porcellus
2.3.1.6 additional information
-
 additional information overview Homo sapiens
2.3.1.6 additional information
-
 additional information overview Rattus norvegicus
2.3.1.6 additional information
-
 additional information overview Bos taurus
2.3.1.6 additional information
-
 additional information overview Oryctolagus cuniculus
2.3.1.6 additional information
-
 additional information overview Columba livia
2.3.1.6 additional information
-
 additional information overview Musa domestica

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.6 acetyl-CoA + choline Homo sapiens
-
 acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline Rattus norvegicus
-
 acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline Bos taurus
-
 acetylcholine + CoA
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.6 Bos taurus
-
-
-
2.3.1.6 Cavia porcellus
-
-
-
2.3.1.6 Columba livia
-
-
-
2.3.1.6 Homo sapiens
-
-
-
2.3.1.6 Musa domestica
-
-
-
2.3.1.6 Oryctolagus cuniculus
-
-
-
2.3.1.6 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.6 brain
-
 Homo sapiens
-
2.3.1.6 brain
-
 Rattus norvegicus
-
2.3.1.6 brain
-
 Bos taurus
-
2.3.1.6 brain
-
 Oryctolagus cuniculus
-
2.3.1.6 brain
-
 Musa domestica
-
2.3.1.6 ganglion autonomic Homo sapiens
-
2.3.1.6 motor spinal root
-
 Cavia porcellus
-
2.3.1.6 motor spinal root
-
 Homo sapiens
-
2.3.1.6 motor spinal root
-
 Rattus norvegicus
-
2.3.1.6 motor spinal root
-
 Bos taurus
-
2.3.1.6 motor spinal root
-
 Oryctolagus cuniculus
-
2.3.1.6 motor spinal root
-
 Columba livia
-
2.3.1.6 motor spinal root
-
 Musa domestica
-
2.3.1.6 nerve trunk preganglionic Cavia porcellus
-
2.3.1.6 nerve trunk preganglionic Homo sapiens
-
2.3.1.6 nerve trunk preganglionic Rattus norvegicus
-
2.3.1.6 nerve trunk preganglionic Bos taurus
-
2.3.1.6 nerve trunk preganglionic Oryctolagus cuniculus
-
2.3.1.6 nerve trunk preganglionic Columba livia
-
2.3.1.6 nerve trunk preganglionic Musa domestica
-
2.3.1.6 retina
-
 Cavia porcellus
-
2.3.1.6 retina
-
 Homo sapiens
-
2.3.1.6 retina
-
 Rattus norvegicus
-
2.3.1.6 retina
-
 Bos taurus
-
2.3.1.6 retina
-
 Oryctolagus cuniculus
-
2.3.1.6 retina
-
 Columba livia
-
2.3.1.6 retina
-
 Musa domestica
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.6 acetyl-CoA + choline
-
 Cavia porcellus acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline
-
 Homo sapiens acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline
-
 Rattus norvegicus acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline
-
 Bos taurus acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline
-
 Oryctolagus cuniculus acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline
-
 Columba livia acetylcholine + CoA
-
 r
2.3.1.6 acetyl-CoA + choline
-
 Musa domestica acetylcholine + CoA
-
 r

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.6 0.008
-
 coenzyme A
-
 Rattus norvegicus
2.3.1.6 0.008
-
 coenzyme A
-
 Bos taurus