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Literature summary extracted from

  • Malathi, K.; Padmanaban, G.; Sarma, P.S.
    Biosynthesis of beta-N-oxalyl-L-alpha,beta-diaminopropionic acid, the Lathyrus sativus neurotoxin (1970), Phytochemistry, 9, 1603-1610.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.58 EDTA slight activation Lathyrus sativus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.58 acetone precipitation with acetone completely inhibits enzyme activity Lathyrus sativus
2.3.1.58 ethanol precipitation with ethanol completely inhibits enzyme activity Lathyrus sativus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.58 0.3
-
 L-2,3-diaminopropionic acid
-
 Lathyrus sativus
2.3.1.58 0.45
-
 oxalyl-CoA
-
 Lathyrus sativus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.58 Lathyrus sativus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.58 60fold Lathyrus sativus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.58 seedling
-
 Lathyrus sativus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.58 additional information
-
-
 Lathyrus sativus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.58 additional information succinyl-CoA and acetyl-CoA are not accepted Lathyrus sativus ?
-
 ?
2.3.1.58 oxalyl-CoA + 2,4-diaminobutyric acid about 20% of activity with L-2,3-diaminopropionic acid Lathyrus sativus CoA + N4-oxalyl-2,4-diaminobutyric acid
-
 ?
2.3.1.58 oxalyl-CoA + L-2,3-diaminopropionic acid
-
 Lathyrus sativus CoA + N3-oxalyl-L-2,3-diaminopropionic acid
-
 ?
2.3.1.58 oxalyl-CoA + L-homoserine about 12% of activity with L-2,3-diaminopropionic acid Lathyrus sativus ?
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.58 37
-
 assay at Lathyrus sativus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.58 7.4 8
-
 Lathyrus sativus