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Literature summary extracted from

  • Brady, R.N.; Di Mari, S.J.; Snell, E.E.
    Biosynthesis of sphingolipid bases. 3. Isolation and characterization of ketonic intermediates in the synthesis of sphingosine and dihydrosphingosine by cell-free extracts of Hansenula ciferri (1969), J. Biol. Chem., 244, 491-496.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.50 endoplasmic reticulum
-
 Wickerhamomyces ciferrii 5783
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.50 palmitoyl-CoA + L-serine Wickerhamomyces ciferrii first step of biosynthesis of sphingolipid bases CoA + 3-dehydro-D-sphinganine + CO2
-
 ir

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.50 Wickerhamomyces ciferrii
-
-
-

Reaction

EC Number Reaction Comment Organism Reaction ID
2.3.1.50 palmitoyl-CoA + L-serine = CoA + 3-dehydro-D-sphinganine + CO2 mechanism Wickerhamomyces ciferrii
a

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.50 palmitoyl-CoA + L-serine
-
 Wickerhamomyces ciferrii CoA + 3-dehydro-D-sphinganine + CO2
-
 ir
2.3.1.50 palmitoyl-CoA + L-serine first step of biosynthesis of sphingolipid bases Wickerhamomyces ciferrii CoA + 3-dehydro-D-sphinganine + CO2
-
 ir

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.50 30
-
 assay at Wickerhamomyces ciferrii