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Literature summary extracted from

  • Yu, P.H.; Boulton, A.A.
    N-Acylation of tyramines: purification and characterization of an arylamine N-acetyltransferase from rat brain and liver (1979), Can. J. Biochem., 57, 1204-1209.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.5 0.05
-
 acetyl-CoA
-
 Rattus norvegicus
2.3.1.5 0.08
-
 octylamine
-
 Rattus norvegicus
2.3.1.5 0.08
-
 3-tyramine
-
 Rattus norvegicus
2.3.1.5 0.11 0.125 serotonin brain Rattus norvegicus
2.3.1.5 0.14 0.145 p-tyramine
-
 Rattus norvegicus
2.3.1.5 0.18
-
 Phenylethylamine
-
 Rattus norvegicus
2.3.1.5 0.28 0.37 4-nitroaniline
-
 Rattus norvegicus
2.3.1.5 0.3
-
 Phenylethylamine
-
 Rattus norvegicus
2.3.1.5 1.3
-
 p-octopamine liver Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.5 25000
-
 gel filtration Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.5 Rattus norvegicus
-
 Wistar
-
2.3.1.5 Rattus norvegicus Wistar
-
 Wistar
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.5
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.5 brain extrapineal distribution Rattus norvegicus
-
2.3.1.5 kidney
-
 Rattus norvegicus
-
2.3.1.5 liver
-
 Rattus norvegicus
-
2.3.1.5 additional information in rat tissues Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.5 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.5 acetyl-CoA + 3-tyramine
-
 Rattus norvegicus CoA + N-acetyl-3-tyramine
-
 ?
2.3.1.5 acetyl-CoA + 4-nitroaniline
-
 Rattus norvegicus CoA + 4-nitroacetanilide
-
 ?
2.3.1.5 acetyl-CoA + beta-phenylethylamine
-
 Rattus norvegicus CoA + N-(2-phenylethyl)-acetaminde
-
 ?
2.3.1.5 acetyl-CoA + beta-phenylethylamine
-
 Rattus norvegicus Wistar CoA + N-(2-phenylethyl)-acetaminde
-
 ?
2.3.1.5 acetyl-CoA + octylamine
-
 Rattus norvegicus CoA + N-acetyloctylamine
-
 ?
2.3.1.5 acetyl-CoA + p-octopamine
-
 Rattus norvegicus CoA + N-acetyloctopamine
-
 ?
2.3.1.5 acetyl-CoA + p-octopamine
-
 Rattus norvegicus Wistar CoA + N-acetyloctopamine
-
 ?
2.3.1.5 acetyl-CoA + p-tyramine
-
 Rattus norvegicus CoA + N-acetyl-p-tyramine
-
 ?
2.3.1.5 acetyl-CoA + p-tyramine
-
 Rattus norvegicus Wistar CoA + N-acetyl-p-tyramine
-
 ?
2.3.1.5 acetyl-CoA + serotonin
-
 Rattus norvegicus CoA + N-acetylserotonin
-
 ?
2.3.1.5 acetyl-CoA + serotonin
-
 Rattus norvegicus Wistar CoA + N-acetylserotonin
-
 ?
2.3.1.5 acetyl-CoA + tryptamine
-
 Rattus norvegicus CoA + N-acetyltryptamine
-
 ?
2.3.1.5 acetyl-CoA + tryptamine
-
 Rattus norvegicus Wistar CoA + N-acetyltryptamine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.5 7.8
-
 tyramine in phosphate buffer Rattus norvegicus