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Literature summary extracted from

  • Lacko, A.G.; Reason, A.J.; Nuckolls, C.; Kudchodkar, B.J.; Nair, M.P.; Sundarrajan, G.; Pritchard, P.H.; Morris, H.R.; Dell, A.
    Characterization of recombinant human plasma lecithin: cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties (1998), J. Lipid Res., 39, 807-820.
    View publication on PubMed

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.43 0.14
-
 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine phospholipase activity Homo sapiens
2.3.1.43 0.19
-
 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine phospholipase activity of recombinant enzyme expressed in baby hamster kidney cells Homo sapiens
2.3.1.43 0.55
-
 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine phospholipase activity of recombinant enzyme devoid of sialic acid, expressed in baby hamster kidney cells Homo sapiens
2.3.1.43 7.44
-
 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine
-
 Homo sapiens
2.3.1.43 10.1
-
 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine recombinant enzyme expressed in baby hamster kidney cells Homo sapiens
2.3.1.43 20.5
-
 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine recombinant enzyme devoid of sialic acid, expressed in baby hamster kidney cells Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.3.1.43 glycoprotein glycans in recombinant enzyme, expressed in baby hamster kidney cells, have bi- and triantennary structures with or without core fucosylation Homo sapiens
2.3.1.43 glycoprotein glycans structure determined by mass spectrometry and linkage analysis Homo sapiens

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.43
-
 Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine + cholesterol
-
 Homo sapiens cholesteryl-1-pyrenebutyrate + lysophosphatidylcholine
-
 ?
2.3.1.43 phosphatidylcholine + sterol
-
 Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
 ?