Literature summary extracted from

Demeester, N.; Castro, G.; Desrumaux, C.; De Geitere, C.; Fruchart, J.C.; Santens, P.; Mulleners, E.; Engelborghs, S.; De Deyn, P.P.; Vandekerckhove, J.; Rosseneu, M.; Labeur, C.
Characterization and functional studies of lipoproteins, lipid transfer proteins, and lecithin:cholesterol acyltransferase in CSF of normal individuals and patients with Alzheimer's disease (2000), J. Lipid Res., 41, 963-974.

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.43	Homo sapiens	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.3.1.43	additional information	-	patients with Alzheimer's disease have lower LCAT activity in cerebrospinal fluid	Homo sapiens

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.43	1,2-bis-(1-pyrenebutanoyl)-sn-glycero-3-phosphocholine + cholesterol	activity assay method based on this reaction	Homo sapiens	cholesteryl-1-pyrenebutyrate + lysophosphatidylcholine	-	?
2.3.1.43	phosphatidylcholine + sterol	-	Homo sapiens	1-acylglycerophosphocholine + sterol ester	-	?

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Release 2023.1 (January 2023)