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Literature summary extracted from

  • Furukawa, Y.; Nishida, T.
    Stability and properties of lecithin-cholesterol acyltransferase (1979), J. Biol. Chem., 254, 7213-7219.
    View publication on PubMed

General Stability

EC Number General Stability Organism
2.3.1.43 apo-A-1, albumin and lecithin-cholesterol vesicles stabilize Homo sapiens
2.3.1.43 inactivation at the air-water interface is prevented by buffered media of low ionic strength Homo sapiens
2.3.1.43 lecithin-cholesterol vesicles stabilize against inactivation to a lesser extent than apo-A-1 Homo sapiens
2.3.1.43 remarkably stable in buffers of very low ionic strength Homo sapiens

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.43 additional information with lecithin-cholesterol vesicles as substrates in the presence of apo-A-1 the enzyme requires an ionic strength of approximately 0.05 for maximal activity Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.43
-
Homo sapiens

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.43 plasma
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 phosphatidylcholine + sterol
-
Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
r

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
2.3.1.43 37
-
0.4 mM phosphate buffer, pH 7.4, ionic strength 0.001: stable up to 6 h, 39 mM phosphate buffer, pH 7.4, ionic strength 0.1: 90% loss of activity Homo sapiens