Literature summary extracted from

Smith, N.B.; Kuksis, A.
Stereochemical substrate requirements of lecithin:cholesterol acyltransferase and its inhibition by enantiomeric lysolecithins (1980), Can. J. Biochem., 58, 1286-1291.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
2.3.1.43	lysophosphatidylcholine	both enantiomers, inhibition reversed by albumin	Homo sapiens
2.3.1.43	Triton X-100	inhibition reversed by albumin	Homo sapiens

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.3.1.43	Homo sapiens	-	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.3.1.43	2-sn-phosphorylcholinediacylglycerol + cholesterol	lower activity than the natural substrate	Homo sapiens	?	-	?
2.3.1.43	additional information	no significant activity with 1-sn-phosphorylcholinediacylglycerol	Homo sapiens	?	-	?
2.3.1.43	phosphatidylcholine + sterol	-	Homo sapiens	1-acylglycerophosphocholine + sterol ester	-	r

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Release 2023.1 (January 2023)