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Literature summary extracted from

  • Fielding, C.J.
    Mechanisms of action of lecithin-cholesterol acyltransferase (1986), Methods Enzymol., 129, 783-790.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.43 apolipoprotein A-I most effective activator Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.43 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.43 plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.43 phosphatidylcholine + sterol wide specificity for acyl acceptor: sterols with a beta-configuration at carbon-3 and trans fused A /B rings Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
 r
2.3.1.43 phosphatidylcholine + sterol water as acyl acceptor: phospholipase activity Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
 r
2.3.1.43 phosphatidylcholine + sterol phosphatidylethanolamine, dimethylphosphatidylethanolamine, lecithins containing different acyl chain lengths and degrees of saturation Homo sapiens 1-acylglycerophosphocholine + sterol ester
-
 r

Synonyms

EC Number Synonyms Comment Organism
2.3.1.43 LAT
-
-
2.3.1.43 LCAT
-
-

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.43 apolipoprotein A1
-
 Homo sapiens