EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.37 | hemin | - |
Cavia porcellus | |
2.3.1.37 | hemin | feed-back inhibition | Rattus norvegicus |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
2.3.1.37 | 0.001 | 0.01 | pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
2.3.1.37 | 0.2 | - |
succinyl-CoA | - |
Rattus norvegicus | |
2.3.1.37 | 19 | - |
glycine | - |
Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.37 | cytosol | - |
Rattus norvegicus | 5829 | - |
2.3.1.37 | mitochondrion | - |
Cavia porcellus | 5739 | - |
2.3.1.37 | mitochondrion | - |
Rattus norvegicus | 5739 | - |
2.3.1.37 | additional information | - |
Cavia porcellus | - |
- |
2.3.1.37 | additional information | processing of enzyme during to targeting to subcellular compartments | Rattus norvegicus | - |
- |
EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|---|
2.3.1.37 | 77000 | - |
mitochondria, gel filtration | Rattus norvegicus |
2.3.1.37 | 178000 | - |
cytosol, gel filtration | Rattus norvegicus |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.37 | Cavia porcellus | - |
- |
- |
2.3.1.37 | Rattus norvegicus | - |
2 isoforms in cytosol and mitochondria | - |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.37 | - |
Cavia porcellus |
2.3.1.37 | partial | Rattus norvegicus |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.37 | liver | - |
Cavia porcellus | - |
2.3.1.37 | liver | porphyric | Rattus norvegicus | - |
EC Number | Storage Stability | Organism |
---|---|---|
2.3.1.37 | -15°C, loss of 25% activity within 10 days | Rattus norvegicus |
2.3.1.37 | 4°C, loss of 40% activity within 10 days | Rattus norvegicus |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.37 | succinyl-CoA + glycine | - |
Cavia porcellus | 5-aminolevulinate + CoA + CO2 | - |
? | |
2.3.1.37 | succinyl-CoA + glycine | - |
Rattus norvegicus | 5-aminolevulinate + CoA + CO2 | - |
? |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.37 | pyridoxal 5'-phosphate | - |
Cavia porcellus | |
2.3.1.37 | pyridoxal 5'-phosphate | - |
Rattus norvegicus |