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Literature summary extracted from

  • Ohashi, A.; Kikuchi, G.
    Purification and some properties of two forms of delta-aminolevulinate synthase from rat liver cytosol (1979), J. Biochem., 85, 239-247.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.37 Mg2+ inhibition of complex form, stimulation of stripped form Rattus norvegicus
2.3.1.37 Na+ inhibition of complex form, stimulation of stripped form Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.37 0.02
-
 succinyl-CoA
-
 Rattus norvegicus
2.3.1.37 12
-
 glycine
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.37 cytosol
-
 Rattus norvegicus 5829
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.37 Mg2+ inhibition of complex form, stimulation of stripped form Rattus norvegicus
2.3.1.37 Na+ inhibition of complex form, stimulation of stripped form Rattus norvegicus

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.37 51000
-
 2 * 51000, cytosol, SDS-PAGE Rattus norvegicus
2.3.1.37 107000 110000 stripped form, sucrose density gradient centrifugation, gel filtration, disc gel electrophoresis Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.37 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.37 2 forms: a complex form and a stripped form that represents a catalytically active protein component of the complex form Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.37 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.37 0.091
-
 purified enzyme Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.37 succinyl-CoA + glycine
-
 Rattus norvegicus 5-aminolevulinate + CoA + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.37 dimer 2 * 51000, cytosol, SDS-PAGE Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.37 pyridoxal 5'-phosphate
-
 Rattus norvegicus