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Literature summary extracted from

  • Viale, A.A.; Wider, E.A.; Battle, A.M.Del C.
    Extraction and characterization of delta-aminolevulinate synthetase (1987), Comp. Biochem. Physiol. B, 87, 607-613.
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.37 additional information 1-2 low molecular-weight compounds which stimulate or stabilize activity found by dialysis of crude extract Rhodopseudomonas palustris

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.37 delta-aminolevuinate product inhibition Rhodopseudomonas palustris
2.3.1.37 additional information cysteine, glutathione, cystine or 2-mercaptoethanol diminishes activity in presence of 5-aminolevulinate Rhodopseudomonas palustris

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.37 additional information
-
 additional information
-
 Rhodopseudomonas palustris

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.37 61000 65000
-
 Rhodopseudomonas palustris

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.37 Rhodopseudomonas palustris
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.37 cell culture
-
 Rhodopseudomonas palustris
-

Storage Stability

EC Number Storage Stability Organism
2.3.1.37 -15°C, not stable Rhodopseudomonas palustris
2.3.1.37 0-4°C, 18 h stable Rhodopseudomonas palustris

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.37 succinyl-CoA + glycine absolute requirement for glycine Rhodopseudomonas palustris 5-aminolevulinate + CoA + CO2
-
 ?
2.3.1.37 succinyl-CoA + glycine absolute requirement for succinyl-CoA Rhodopseudomonas palustris 5-aminolevulinate + CoA + CO2
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.37 monomer 1 * 61000-65000 Rhodopseudomonas palustris

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.37 37
-
-
 Rhodopseudomonas palustris

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.37 7.5
-
-
 Rhodopseudomonas palustris

Cofactor

EC Number Cofactor Comment Organism Structure
2.3.1.37 pyridoxal 5'-phosphate
-
 Rhodopseudomonas palustris