Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Marco, C.; Morillas, L.G.; Garcia-Peregrin, E.
    Acyl coenzyme A:cholesterol acyltransferase in neonatal chick brain (1986), Biochim. Biophys. Acta, 875, 599-604.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.26 albumin stimulates Gallus gallus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.26 bovine serum albumin inhibits at high concentrations Gallus gallus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.26 microsome
-
 Gallus gallus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.26 Gallus gallus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.26 brain neonatal Gallus gallus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.26 additional information
-
 overview: specific activities in microsomes stored at -40°C for up to 6 weeeks Gallus gallus
2.3.1.26 0.0000178
-
 microsomal preparation Gallus gallus

Storage Stability

EC Number Storage Stability Organism
2.3.1.26 -40°C, stable for several weeks Gallus gallus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.26 acyl-CoA + cholesterol
-
 Gallus gallus CoA + cholesterol ester
-
 ?
2.3.1.26 palmitoyl-CoA + cholesterol
-
 Gallus gallus CoA + cholesteryl palmitate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.26 37
-
 assay at Gallus gallus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
2.3.1.26 5.6 7.4 2fold higher activity at pH 5.6 than at pH 7.4 Gallus gallus