Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Fyrst, H.; Pham, D.V.; Lubin, B.H.; Kuypers, F.A.
    Formation of vesicles by the action of acyl-CoA:1-acyllsophosphatidylcholine acyltransferase from rat liver microsomes: optimal solubilization conditions and analysis of lipid composition and enzyme activity (1996), Biochemistry, 35, 2644-2650.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.23 partially purified from vesicles Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.23 additional information
-
 activity is different in either its microsomal environment or vesicles and is affected by the phospholipid molecular species environment Rattus norvegicus
2.3.1.23 0.01
-
 partially purified enzyme, 1-palmitoyl-glycero-3-phosphocholine as substrate Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoethanolamine 57% and 6% of activity with 1-acyl-sn-glycero-3-phosphocholine in microsomes and phosphatidylcholine vesicles respectively Rattus norvegicus CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine
-
 ?
2.3.1.23 arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoinositol 35% and 8% of activity with 1-acyl-sn-glycero-3-phosphocholine in microsomes and phosphatidylcholine vesicles respectively Rattus norvegicus CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
-
 ?
2.3.1.23 arachidonoyl-CoA + 1-acyl-sn-glycero-3-phosphoserine 99% and 22% of activity with 1-acyl-sn-glycero-3-phosphocholine in microsomes and phosphatidylcholine vesicles respectively Rattus norvegicus CoA + 1-acyl-2-arachidonoyl-sn-glycero-3-phosphoserine
-
 ?

Subunits

EC Number Subunits Comment Organism
2.3.1.23 More one major protein of 21000 Da after purification of the enzyme from vesicles Rattus norvegicus