Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Weltzien, H.U.; Richter, G.; Ferber, E.
    Detergent properties of water-soluble choline phosphatides. Selective solubilization of acyl-CoA:lysolecithin acyltransferase from thymocyte plasma membranes (1979), J. Biol. Chem., 254, 3652-3657.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.23 1-decyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 1-dodecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 1-hexadecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 1-octadecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 1-tetradecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 Berol-043 0.25%, 90% inhibition Bos taurus
2.3.1.23 cholate 1%, 90% inhibition Bos taurus
2.3.1.23 deoxycholate 0.25%, 90% inhibition Bos taurus
2.3.1.23 glycocholate 0.2%, 90% inhibition Bos taurus
2.3.1.23 lysolecithin analogs above 0.1 mM, C10-C16, competitive inhibition Bos taurus
2.3.1.23 Nonidet P-40 0.25%, 90% inhibition Bos taurus
2.3.1.23 Triton X-100 0.05% Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.23 0.0065
-
 1-palmitoyl-sn-glycero-3-phosphocholine
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 membrane
-
 Bos taurus 16020
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Bos taurus
-
 calf
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.23 solubilization and selective extraction with lysolecithin analogs at low concentration Bos taurus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 thymocyte
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.23 0.028
-
-
 Bos taurus

Storage Stability

EC Number Storage Stability Organism
2.3.1.23 -20°C, at least 2 weeks Bos taurus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 palmitoyl-CoA + 1-palmitoyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1,2-dipalmitoyl-sn-glycero-3-phosphocholine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.23 37
-
-
 Bos taurus

Ki Value [mM]

EC Number Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
2.3.1.23 0.08
-
 1-hexadecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 0.27
-
 1-octadecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 0.275
-
 1-tetradecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 0.375
-
 1-dodecyl propanediol-3-phosphorylcholine
-
 Bos taurus
2.3.1.23 1.4
-
 1-decyl propanediol-3-phosphorylcholine
-
 Bos taurus