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Literature summary extracted from

  • Lands, W.E.M.; Hart, P.
    Metabolism of glycerolipids. VI. Specificities of acyl-CoA: phospholipid acyltransferases (1965), J. Biol. Chem., 240, 1905-1911.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.62 bovine serum albumin fatty acid deficient, 2 mg per ml Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.23 additional information not inhibited by diisopropylfluorophosphate Bos taurus
2.3.1.23 additional information not inhibited by diisopropylfluorophosphate Cavia porcellus
2.3.1.23 additional information not inhibited by diisopropylfluorophosphate Rattus norvegicus
2.3.1.23 additional information not inhibited by diisopropylfluorophosphate Sus scrofa
2.3.1.23 Phosphorylhomocholine
-
 Mesocricetus auratus
2.3.1.23 Phosphorylhomocholine
-
 Rattus norvegicus
2.3.1.62 additional information
-
 Cavia porcellus
2.3.1.62 additional information not inhibited by iodoacetamide Rattus norvegicus
2.3.1.62 N-ethylmaleimide not inhibitory Rattus norvegicus
2.3.1.62 p-chloromercuribenzoate above 2.0 mM Rattus norvegicus
2.3.1.62 palmitoyl-CoA bovine serum albumin or boiled microsomal preparation restores activity Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.23 additional information
-
 additional information
-
 Cavia porcellus
2.3.1.23 additional information
-
 additional information
-
 Rattus norvegicus
2.3.1.23 additional information
-
 additional information
-
 Sus scrofa
2.3.1.23 additional information
-
 additional information
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.23 microsome
-
 Cavia porcellus
-
-
2.3.1.23 microsome
-
 Rattus norvegicus
-
-
2.3.1.23 microsome
-
 Sus scrofa
-
-
2.3.1.23 microsome
-
 Bos taurus
-
-
2.3.1.23 microsome
-
 Mesocricetus auratus
-
-
2.3.1.62 microsome
-
 Cavia porcellus
-
-
2.3.1.62 microsome
-
 Rattus norvegicus
-
-
2.3.1.62 microsome
-
 Sus scrofa
-
-
2.3.1.62 microsome
-
 Bos taurus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine Cavia porcellus reaction in phosphatidylcholine metabolism CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine Rattus norvegicus reaction in phosphatidylcholine metabolism CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine Sus scrofa reaction in phosphatidylcholine metabolism CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine Bos taurus reaction in phosphatidylcholine metabolism CoA + phosphatidylcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.23 Bos taurus
-
-
-
2.3.1.23 Cavia porcellus
-
-
-
2.3.1.23 Mesocricetus auratus
-
-
-
2.3.1.23 Rattus norvegicus
-
-
-
2.3.1.23 Sus scrofa
-
-
-
2.3.1.62 Bos taurus
-
-
-
2.3.1.62 Cavia porcellus
-
-
-
2.3.1.62 Rattus norvegicus
-
-
-
2.3.1.62 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.23 heart
-
 Cavia porcellus
-
2.3.1.23 heart
-
 Rattus norvegicus
-
2.3.1.23 heart
-
 Sus scrofa
-
2.3.1.23 heart
-
 Bos taurus
-
2.3.1.23 intestine
-
 Rattus norvegicus
-
2.3.1.23 liver
-
 Cavia porcellus
-
2.3.1.23 liver
-
 Rattus norvegicus
-
2.3.1.23 liver
-
 Sus scrofa
-
2.3.1.23 liver
-
 Bos taurus
-
2.3.1.62 brain
-
 Rattus norvegicus
-
2.3.1.62 intestine
-
 Rattus norvegicus
-
2.3.1.62 liver
-
 Cavia porcellus
-
2.3.1.62 liver
-
 Rattus norvegicus
-
2.3.1.62 liver
-
 Sus scrofa
-
2.3.1.62 liver
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Mesocricetus auratus CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 linoleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 myristoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-acyl-2-myristoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 myristoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-acyl-2-myristoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 myristoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-acyl-2-myristoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 myristoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-acyl-2-myristoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 oleoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 palmitoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-acyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 palmitoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-acyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 palmitoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-acyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 palmitoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-acyl-2-palmitoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 stearoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-acyl-2-stearoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 stearoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-acyl-2-stearoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 stearoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-acyl-2-stearoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.23 stearoyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-acyl-2-stearoyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine reaction in phosphatidylcholine metabolism Cavia porcellus CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine reaction in phosphatidylcholine metabolism Rattus norvegicus CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine reaction in phosphatidylcholine metabolism Sus scrofa CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine reaction in phosphatidylcholine metabolism Bos taurus CoA + phosphatidylcholine
-
 ?
2.3.1.62 linoleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-linoleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 linoleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-linoleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 linoleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-linoleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 linoleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-linoleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 myristoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-myristoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 myristoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-myristoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 myristoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-myristoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 myristoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-myristoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 oleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 oleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 oleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 oleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 palmitoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 palmitoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 palmitoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 palmitoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 stearoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Cavia porcellus CoA + 1-stearoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 stearoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Rattus norvegicus CoA + 1-stearoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 stearoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Sus scrofa CoA + 1-stearoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 stearoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Bos taurus CoA + 1-stearoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.23 7 8
-
 Cavia porcellus
2.3.1.23 7 8
-
 Rattus norvegicus
2.3.1.23 7 8
-
 Sus scrofa
2.3.1.23 7 8
-
 Bos taurus