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Literature summary extracted from

  • Bhat, B.G.; Bardes, E.S.G.; Coleman, R.A.
    Solubilization and partial purification of neonatally expressed rat hepatic microsomal monoacylglycerol acyltransferase (1993), Arch. Biochem. Biophys., 300, 663-669.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.22 Phospholipid phosphatidylcholine/phosphatidylserine at 0.025 mg/ml stimulates 80% Rattus norvegicus
2.3.1.22 sn-1,2-dioleoylglycerol 0.3 mM, stimulates 44% Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.22 beta-octylglucoside 2.5% Rattus norvegicus
2.3.1.22 CHAPS 1.5% Rattus norvegicus
2.3.1.22 taurocholate 2% Rattus norvegicus
2.3.1.22 Triton X-100 no inhibition Rattus norvegicus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.22 0.0065
-
 palmitoyl-CoA
-
 Rattus norvegicus
2.3.1.22 0.0071
-
 sn-2-monolinolenoylglycerol
-
 Rattus norvegicus
2.3.1.22 0.011
-
 sn-2-monolinoleoylglycerol
-
 Rattus norvegicus
2.3.1.22 0.021
-
 sn-2-monooleoylglycerol
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.22 microsome
-
 Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.22 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.22 partial Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.22 liver neonatal Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.22 1.219
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.22 acyl-CoA + sn-2-monolinolenoylglycerol in preference to sn-2-monooleoylglycerol Rattus norvegicus CoA + 1-acyl-2-linolenoylglycerol
-
 ?
2.3.1.22 acyl-CoA + sn-2-monolinoleoylglycerol in preference to sn-2-monooleoylglycerol Rattus norvegicus CoA + 1-acyl-2-linoleoylglycerol
-
 ?
2.3.1.22 fatty acyl-CoA + sn-2-monoacylglycerol
-
 Rattus norvegicus CoA + 1,2-diacylglycerol
-
 ?
2.3.1.22 palmitoyl-CoA + sn-2-monooleoylglycerol
-
 Rattus norvegicus CoA + 1(3)-palmitoyl-2-oleoylglycerol
-
 ?