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Literature summary extracted from

  • Ishii, S.; Ishii, H.; Watanabe, T.; Suga, T.
    Purification and properties of peroxisomal carnitine palmitoyltransferase in chick embryo liver (1987), Biochim. Biophys. Acta, 924, 530-542.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 Trypsin peroxisomal and mitochondrial isozymes Gallus gallus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.21 additional information
-
 additional information overview: Km values for several acyl-CoA and acyl-carnitine substrates, both reaction directions, peroxisomal and mitochondrial isozyme Gallus gallus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 peroxisome
-
 Gallus gallus 5777
-

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.3.1.21 64000
-
 1 * 64000, peroxisomes, SDS-PAGE Gallus gallus
2.3.1.21 66000
-
 peroxisomes, gel filtration Gallus gallus
2.3.1.21 69000
-
 4 * 69000, mitochondria Gallus gallus
2.3.1.21 260000
-
 mitochondria, gel filtration Gallus gallus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Gallus gallus
-
 CoA + L-acylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Gallus gallus
-
 embryo
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.21 peroxisomal Gallus gallus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 liver
-
 Gallus gallus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.21 additional information
-
-
 Gallus gallus
2.3.1.21 4.65
-
 purified mitochondrial enzyme Gallus gallus
2.3.1.21 13.2
-
 purified peroxisomal enzyme Gallus gallus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Gallus gallus CoA + L-acylcarnitine
-
 ?
2.3.1.21 acyl-CoA + L-carnitine substrate specificity Gallus gallus CoA + L-acylcarnitine reverse reaction: acyl-CoA substrates are C4 to C18 acylcarnitines r
2.3.1.21 acyl-CoA + L-carnitine C4 to C18 acyl-CoAs Gallus gallus CoA + L-acylcarnitine reverse reaction: acyl-CoA substrates are C4 to C18 acylcarnitines r
2.3.1.21 palmitoyl-CoA + L-carnitine
-
 Gallus gallus CoA + L-palmitoylcarnitine
-
 r

Subunits

EC Number Subunits Comment Organism
2.3.1.21 monomer 1 * 64000, peroxisomes, SDS-PAGE Gallus gallus
2.3.1.21 tetramer 4 * 69000, mitochondria Gallus gallus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.21 6.5 8 mitochondrial Gallus gallus
2.3.1.21 8.5
-
 peroxisomal Gallus gallus