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Literature summary extracted from

  • Murthy, M.S.R.; Pande, S.V.
    Some differences in the properties of carnitine palmitoyltransferase activities of the mitochondrial outer and inner membranes (1987), Biochem. J., 248, 727-733.
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.21 cholate activates only CPTi Rattus norvegicus
2.3.1.21 octyl glucoside only CPTi Rattus norvegicus
2.3.1.21 Phosphatidylcholine liposomes only CPTi Rattus norvegicus
2.3.1.21 Triton X-100 only CPTi Rattus norvegicus
2.3.1.21 Tween 20 activates only CPTi Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.21 cholate only CPTo Rattus norvegicus
2.3.1.21 Digitonin CPTo and slightly CPTi Rattus norvegicus
2.3.1.21 malonyl-CoA
-
 Rattus norvegicus
2.3.1.21 octyl glucoside only CPTo Rattus norvegicus
2.3.1.21 Triton X-100 only CPTo Rattus norvegicus
2.3.1.21 Tween 20 only CPTo at 2% and above Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.21 mitochondrial inner membrane enzyme from outer and from inner membrane have different properties Rattus norvegicus 5743
-
2.3.1.21 mitochondrial outer membrane enzyme from outer and from inner membrane have different properties Rattus norvegicus 5741
-
2.3.1.21 mitochondrion
-
 Rattus norvegicus 5739
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine Rattus norvegicus
-
 CoA + L-acylcarnitine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.21 Rattus norvegicus
-
 enzyme forms CPTo and CPTi from outer and inner mitochondrial membrane
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.21 erythrocyte
-
 Rattus norvegicus
-
2.3.1.21 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.21 acyl-CoA + L-carnitine
-
 Rattus norvegicus CoA + L-acylcarnitine
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.3.1.21 CPTi inner, initially latent carnitine transferase Rattus norvegicus
2.3.1.21 CPTo
-
-