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Literature summary extracted from

  • Campuzano, I.D.G.; Shoolingin-Jordan, P.M.
    Incubation of 6-methylsalicylic acid synthase with alternative starter units in the absence of NADPH and the identification of the resulting triaceticacid lactones (1998), Biochem. Soc. Trans., 26, S284.
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.165 Penicillium griseofulvum
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Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.165 acetoacetyl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-methyl triacetic acid lactone + CoA
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 ?
2.3.1.165 acetyl-CoA + malonyl-CoA
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 Penicillium griseofulvum triacetic lactone
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 ?
2.3.1.165 acetyl-CoA + malonyl-CoA + NADPH
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 Penicillium griseofulvum 6-methylsalicylate + CoA + CO2 + NADP+
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 ?
2.3.1.165 butyryl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-propyl triacetic acid lactone + CoA
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 ?
2.3.1.165 crotonyl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-(2-propene) triacetic acid lactone + CoA
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 ?
2.3.1.165 heptanoyl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-hexyl triacetic acid lactone + CoA
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 ?
2.3.1.165 hexanoyl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-pentyl triacetic acid lactone + CoA
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 ?
2.3.1.165 propionyl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-ethyl triacetic acid lactone + CoA
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 ?
2.3.1.165 valeryl-CoA + malonyl-CoA 5% of the rate of 6-methylsalicylic acid synthesis Penicillium griseofulvum 6-butyl triacetic acid lactone + CoA
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