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Literature summary extracted from

  • Yamada, K.; Okuyama, H.; Endo, Y.; Ikezawa, H.
    Acyltransferase systems involved in phospholipid metabolism in Saccharomyces cerevisiae (1977), Arch. Biochem. Biophys., 183, 281-289.
    View publication on PubMed

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.15 microsome
-
 Saccharomyces cerevisiae
-
-
2.3.1.15 mitochondrion
-
 Saccharomyces cerevisiae 5739
-
2.3.1.23 microsome
-
 Saccharomyces cerevisiae
-
-
2.3.1.51 membrane
-
 Saccharomyces cerevisiae 16020
-
2.3.1.51 microsome
-
 Saccharomyces cerevisiae
-
-
2.3.1.51 mitochondrion the presence of the enzyme in the mitochondrial fraction cannot be explained by the contamination of microsomes in this fraction Saccharomyces cerevisiae 5739
-
2.3.1.52 membrane
-
 Saccharomyces cerevisiae 16020
-
2.3.1.62 microsome
-
 Saccharomyces cerevisiae
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine Saccharomyces cerevisiae reaction in phosphatidylcholine metabolism CoA + phosphatidylcholine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.15 Saccharomyces cerevisiae
-
 OC-2
-
2.3.1.15 Saccharomyces cerevisiae OC-2
-
 OC-2
-
2.3.1.23 Saccharomyces cerevisiae
-
 OC-2
-
2.3.1.23 Saccharomyces cerevisiae OC-2
-
 OC-2
-
2.3.1.51 Saccharomyces cerevisiae
-
 OC-2
-
2.3.1.51 Saccharomyces cerevisiae OC-2
-
 OC-2
-
2.3.1.52 Saccharomyces cerevisiae
-
 OC-2
-
2.3.1.52 Saccharomyces cerevisiae OC-2
-
 OC-2
-
2.3.1.62 Saccharomyces cerevisiae
-
 OC-2
-
2.3.1.62 Saccharomyces cerevisiae OC-2
-
 OC-2
-

Storage Stability

EC Number Storage Stability Organism
2.3.1.52 -70°C, membrane preparation, at least 2 months Saccharomyces cerevisiae
2.3.1.62 -70°C, membrane preparation, at least 2 months Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate broad specificity Saccharomyces cerevisiae CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate broad specificity Saccharomyces cerevisiae OC-2 CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 myristoyl-CoA + sn-glycerol 3-phosphate i.e. tetradecanoyl-CoA Saccharomyces cerevisiae CoA + 1-myristoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 myristoyl-CoA + sn-glycerol 3-phosphate i.e. tetradecanoyl-CoA Saccharomyces cerevisiae OC-2 CoA + 1-myristoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 oleoyl-CoA + sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 oleoyl-CoA + sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae OC-2 CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae OC-2 CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 stearoyl-CoA + sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-stearoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 stearoyl-CoA + sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae OC-2 CoA + 1-stearoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.23 acyl-CoA + 1-acyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae CoA + 1,2-diacyl-sn-glycero-3-phosphocholine
-
 r
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate i.e. lysophosphatidic acid, highly specific for 1-acyl-sn-glycerol 3-phosphate, catalyzes acylation of position 2 hydroxyl-group Saccharomyces cerevisiae CoA + 1,2-diacyl-sn-glycerol 3-phosphate i.e. phosphatidic acid ?
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate effect of substrate concentration Saccharomyces cerevisiae CoA + 1,2-diacyl-sn-glycerol 3-phosphate i.e. phosphatidic acid ?
2.3.1.51 acyl-CoA + 1-acyl-sn-glycerol 3-phosphate the enzyme utilizes saturated and unsaturated acyl-CoAs at comparable rates Saccharomyces cerevisiae CoA + 1,2-diacyl-sn-glycerol 3-phosphate i.e. phosphatidic acid ?
2.3.1.51 acyl-CoA + 2-acyl-sn-glycerol 3-phosphate the rate of CoA-liberation is much lower than with 1-acyl-sn-glycerol 3-phosphate Saccharomyces cerevisiae CoA + ?
-
 ?
2.3.1.51 additional information very broad specificity for acyl-CoAs, the enzyme does not seem to discriminate strictly the cis and trans configurations or the position of double bond in the fatty acyl moiety Saccharomyces cerevisiae ?
-
 ?
2.3.1.51 oleoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-acyl-2-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.51 palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.52 oleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-oleoyl-2-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.52 palmitoyl-CoA + 2-acyl-sn-glycerol 3-phosphate
-
 Saccharomyces cerevisiae CoA + 1-palmitoyl-2-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae CoA + phosphatidylcholine
-
 ?
2.3.1.62 acyl-CoA + 2-acyl-sn-glycero-3-phosphocholine reaction in phosphatidylcholine metabolism Saccharomyces cerevisiae CoA + phosphatidylcholine
-
 ?
2.3.1.62 oleoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae CoA + 1-oleoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?
2.3.1.62 palmitoyl-CoA + 2-acyl-sn-glycero-3-phosphocholine
-
 Saccharomyces cerevisiae CoA + 1-palmitoyl-2-acyl-sn-glycero-3-phosphocholine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.52 25
-
 assay at Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.23 7 9
-
 Saccharomyces cerevisiae
2.3.1.51 7 9 broad Saccharomyces cerevisiae