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Literature summary extracted from

  • Monroy, G.; Chroboczek Kelker, H.; Pullman, M.E.
    Partial purification and properties of an acyl coenzyme A:sn-glycerol 3-phosphate acyltransferase from rat liver mitochondria (1973), J. Biol. Chem., 248, 2845-2852.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.15 asolectin i.e. crude mixture of soybean phospholipids, activation of mitochondrial enzyme Rattus norvegicus
2.3.1.15 bovine serum albumin
-
 Rattus norvegicus
2.3.1.15 phosphatidylcholine
-
 Rattus norvegicus
2.3.1.15 phosphatidylserine activation of mitochondrial enzyme Rattus norvegicus
2.3.1.15 Phospholipids
-
 Rattus norvegicus

General Stability

EC Number General Stability Organism
2.3.1.15 asolectin stabilizes cholate-containing preparations Rattus norvegicus
2.3.1.15 bovine serum albumin stabilizes Rattus norvegicus
2.3.1.15 cholate inactivates during storage Rattus norvegicus
2.3.1.15 repeated freezing and thawing inactivates Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.15 1-palmitoyl-sn-glycerol 3-phosphate
-
 Rattus norvegicus
2.3.1.15 cardiolipin
-
 Rattus norvegicus
2.3.1.15 cholate
-
 Rattus norvegicus
2.3.1.15 diacylglycerophosphate
-
 Rattus norvegicus
2.3.1.15 Monoacylglycerophosphate
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.15 mitochondrial membrane membrane-bound Rattus norvegicus 31966
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.3.1.15 Ca2+ activation of microsomal and mitochondrial enzyme Rattus norvegicus
2.3.1.15 Co2+
-
 Rattus norvegicus
2.3.1.15 Mg2+
-
 Rattus norvegicus
2.3.1.15 Mn2+
-
 Rattus norvegicus

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.15 Rattus norvegicus
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.3.1.15 lipoprotein
-
 Rattus norvegicus

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.15 mitochondrial enzyme, cholate, ammonium sulfate, partial purification Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.15 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.15 0.0138
-
-
 Rattus norvegicus

Storage Stability

EC Number Storage Stability Organism
2.3.1.15 -70°C, 2 months after the removal of cholate Rattus norvegicus
2.3.1.15 -70°C, 35% loss of activity after 2 days Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate exclusively acylates glycerol 3-phosphate at the C-1-position Rattus norvegicus CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 acyl-CoA + sn-glycerol 3-phosphate no acyl-donors are hexanoyl-CoA, octanoyl-CoA Rattus norvegicus CoA + 1-acyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 linoleoyl-CoA + sn-glycerol 3-phosphate 2% of activity with palmitoyl-CoA Rattus norvegicus CoA + 1-linoleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 myristoyl-CoA + sn-glycerol 3-phosphate i.e. tetradecanoyl-CoA Rattus norvegicus CoA + 1-myristoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 n-decanoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-n-decanoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 oleoyl-CoA + sn-glycerol 3-phosphate 7% of activity with palmitoyl-CoA Rattus norvegicus CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 stearoyl-CoA + sn-glycerol 3-phosphate poor substrate Rattus norvegicus CoA + 1-stearoyl-sn-glycerol 3-phosphate
-
 ?