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Literature summary extracted from

  • Bates, E.J.; Saggerson, E.D.
    A study of the glycerol phosphate acyltransferase and dihydroxyacetone phosphate acyltransferase activities in rat liver mitochondrial and microsomal fractions. Relative distribution in parenchymal and non-parenchymal cells, effects of N-ethylmaleimide, palmitoyl-coenzyme A concentration, starvation, adrenalectomy and anti-insulin serum treatment (1979), Biochem. J., 182, 751-762.
    View publication on PubMedView publication on EuropePMC

General Stability

EC Number General Stability Organism
2.3.1.42 freezing, crude preparation, stable to Rattus norvegicus

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.15 additional information mitochondrial enzyme, not inhibited by N-ethylmaleimide Rattus norvegicus
2.3.1.15 N-ethylmaleimide 0.5-10 mM, 80-90% inhibition of microsomal acyltransferase, mitochondrial acyltransferase is not inhibited Rattus norvegicus
2.3.1.15 palmitoyl-CoA microsomal enzyme, above 0.1 mM Rattus norvegicus
2.3.1.42 N-ethylmaleimide no inhibition; not peroxisomal enzyme; weak Cavia porcellus
2.3.1.42 N-ethylmaleimide no inhibition; not peroxisomal enzyme; weak Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.3.1.15 microsome
-
 Rattus norvegicus
-
-
2.3.1.15 mitochondrion
-
 Rattus norvegicus 5739
-
2.3.1.42 additional information subcellular distribution Cavia porcellus
-
-
2.3.1.42 additional information subcellular distribution Rattus norvegicus
-
-

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.15 Rattus norvegicus
-
 Sprague-Dawley strain
-
2.3.1.15 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley strain
-
2.3.1.42 Cavia porcellus
-
 male Dunkin and Hartley strain
-
2.3.1.42 Cavia porcellus Hartley
-
 male Dunkin and Hartley strain
-
2.3.1.42 Rattus norvegicus
-
 male Sprague-Dawley
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.15 liver
-
 Rattus norvegicus
-
2.3.1.42 liver
-
 Cavia porcellus
-
2.3.1.42 liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2.3.1.42 additional information
-
-
 Cavia porcellus
2.3.1.42 additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.15 palmitoyl-CoA + sn-glycerol 3-phosphate
-
 Rattus norvegicus Sprague-Dawley CoA + 1-palmitoyl-sn-glycerol 3-phosphate
-
 ?
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate
-
 Cavia porcellus CoA + acyldihydroxyacetone phosphate i.e. acylglycerone phosphate ?
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus CoA + acyldihydroxyacetone phosphate i.e. acylglycerone phosphate ?
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus Sprague-Dawley CoA + acyldihydroxyacetone phosphate i.e. acylglycerone phosphate ?
2.3.1.42 acyl-CoA + dihydroxyacetone phosphate
-
 Cavia porcellus Hartley CoA + acyldihydroxyacetone phosphate i.e. acylglycerone phosphate ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate
-
 Cavia porcellus CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate
-
 Rattus norvegicus Sprague-Dawley CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?
2.3.1.42 palmitoyl-CoA + dihydroxyacetone phosphate
-
 Cavia porcellus Hartley CoA + monopalmitoyldihydroxyacetone phosphate
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.42 30
-
 assay at Cavia porcellus
2.3.1.42 30
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.42 7.4
-
-
 Cavia porcellus
2.3.1.42 7.4
-
 assay at Rattus norvegicus