EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.15 | Polymyxin B | activation of mitochondrial enzyme, inhibition of microsomal enzyme | Rattus norvegicus |
EC Number | General Stability | Organism |
---|---|---|
2.3.1.15 | phospholipids stabilize | Escherichia coli |
2.3.1.15 | phospholipids stabilize | Rattus norvegicus |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
2.3.1.15 | 5,5'-dithiobis(2-nitro-benzoate) | - |
Escherichia coli | |
2.3.1.15 | 5,5'-dithiobis(2-nitro-benzoate) | inhibition of microsomal enzyme, mitochondrial enzyme is not inhibited | Rattus norvegicus | |
2.3.1.15 | acetone | inhibition of microsomal enzyme | Rattus norvegicus | |
2.3.1.15 | iodoacetamide | strong inhibition of microsomal enzyme, mitochondrial enzyme is not inhibited | Rattus norvegicus | |
2.3.1.15 | MgCl2 | inhibition of microsomal enzyme | Rattus norvegicus | |
2.3.1.15 | N-ethylmaleimide | - |
Escherichia coli | |
2.3.1.15 | N-ethylmaleimide | strong inhibition of microsomal isozyme, mitochondrial enzyme is not inhibited | Rattus norvegicus | |
2.3.1.15 | Polymyxin B | 0.5 mg/ml, approx. 75% inhibition of microsomal enzyme, slight stimulation of mitochondrial enzyme | Rattus norvegicus | |
2.3.1.15 | Triton X-100 | - |
Escherichia coli | |
2.3.1.15 | Triton X-100 | - |
Rattus norvegicus | |
2.3.1.42 | glycerol 3-phosphate | adipocyte | Rattus norvegicus | |
2.3.1.42 | N-ethylmaleimide | not peroxisomal enzyme | Oryctolagus cuniculus | |
2.3.1.42 | N-ethylmaleimide | not peroxisomal enzyme | Rattus norvegicus | |
2.3.1.51 | additional information | no inhibition by sulfhydryl reagents, 1-acylglycerol 3-phosphoethanol, 1-acylglycerol 3-phosphoethanolamine, 1-acylglycerol 3-phosphodimethylethanolamine, 1-acylglycerol 3-choline | Rattus norvegicus |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
2.3.1.15 | microsome | membrane-bound | Rattus norvegicus | - |
- |
2.3.1.15 | mitochondrial membrane | membrane-bound | Rattus norvegicus | 31966 | - |
2.3.1.20 | microsome | active site on cytoplasmic surface | Rattus norvegicus | - |
- |
2.3.1.42 | microsome | - |
Rattus norvegicus | - |
- |
2.3.1.42 | microsome | - |
Oryctolagus cuniculus | - |
- |
2.3.1.42 | mitochondrion | outer membrane | Rattus norvegicus | 5739 | - |
2.3.1.42 | peroxisome | - |
Rattus norvegicus | 5777 | - |
2.3.1.42 | peroxisome | - |
Oryctolagus cuniculus | 5777 | - |
2.3.1.51 | microsome | not rat liver peroxisomes | Rattus norvegicus | - |
- |
2.3.1.51 | microsome | intrinsic membrane protein, cytoplasmic surface | Rattus norvegicus | - |
- |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.20 | acyl-CoA + 1,2-diacylglycerol | Rattus norvegicus | last reaction in triacylglycerol synthesis | CoA + triacylglycerol | - |
? | |
2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate | Rattus norvegicus | peroxisomal enzyme involved in ether lipid biosynthesis | CoA + monopalmitoyldihydroxyacetone phosphate | - |
? | |
2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate | Oryctolagus cuniculus | peroxisomal enzyme involved in ether lipid biosynthesis | CoA + monopalmitoyldihydroxyacetone phosphate | - |
? | |
2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | Rattus norvegicus | involved in phospholipid biosynthesis | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
2.3.1.15 | Escherichia coli | - |
- |
- |
2.3.1.15 | Rattus norvegicus | - |
- |
- |
2.3.1.20 | Rattus norvegicus | - |
- |
- |
2.3.1.42 | Oryctolagus cuniculus | - |
- |
- |
2.3.1.42 | Rattus norvegicus | - |
- |
- |
2.3.1.51 | Rattus norvegicus | - |
- |
- |
EC Number | Posttranslational Modification | Comment | Organism |
---|---|---|---|
2.3.1.15 | side-chain modification | activity of microsomal enzyme is probably regulated by phosphorylation-dephosphorylation | Rattus norvegicus |
EC Number | Purification (Comment) | Organism |
---|---|---|
2.3.1.15 | Triton X-100-solubilized | Escherichia coli |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
2.3.1.15 | liver | - |
Rattus norvegicus | - |
2.3.1.15 | mammary gland | lactating | Rattus norvegicus | - |
2.3.1.15 | additional information | distribution, overview | Escherichia coli | - |
2.3.1.15 | additional information | distribution, overview | Rattus norvegicus | - |
2.3.1.20 | adipocyte | - |
Rattus norvegicus | - |
2.3.1.20 | intestinal mucosa | - |
Rattus norvegicus | - |
2.3.1.20 | liver | - |
Rattus norvegicus | - |
2.3.1.20 | mammary gland | - |
Rattus norvegicus | - |
2.3.1.20 | additional information | distribution, overview | Rattus norvegicus | - |
2.3.1.42 | adipocyte | - |
Rattus norvegicus | - |
2.3.1.42 | additional information | distribution, overview | Rattus norvegicus | - |
2.3.1.42 | additional information | distribution, overview | Oryctolagus cuniculus | - |
2.3.1.51 | liver | - |
Rattus norvegicus | - |
2.3.1.51 | lung | - |
Rattus norvegicus | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
2.3.1.15 | acyl-CoA + sn-glycerol 3-phosphate | saturated acyl-CoAs preferred | Escherichia coli | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.15 | acyl-CoA + sn-glycerol 3-phosphate | saturated acyl-CoAs preferred | Rattus norvegicus | CoA + 1-acyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.20 | acyl-CoA + 1,2-diacylglycerol | last reaction in triacylglycerol synthesis | Rattus norvegicus | CoA + triacylglycerol | - |
? | |
2.3.1.42 | acyl-CoA + dihydroxyacetone phosphate | - |
Rattus norvegicus | CoA + acyldihydroxyacetone phosphate | i.e. acylglycerone phosphate | ? | |
2.3.1.42 | acyl-CoA + dihydroxyacetone phosphate | - |
Oryctolagus cuniculus | CoA + acyldihydroxyacetone phosphate | i.e. acylglycerone phosphate | ? | |
2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate | peroxisomal enzyme involved in ether lipid biosynthesis | Rattus norvegicus | CoA + monopalmitoyldihydroxyacetone phosphate | - |
? | |
2.3.1.42 | palmitoyl-CoA + dihydroxyacetone phosphate | peroxisomal enzyme involved in ether lipid biosynthesis | Oryctolagus cuniculus | CoA + monopalmitoyldihydroxyacetone phosphate | - |
? | |
2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | - |
Rattus norvegicus | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | i.e. phosphatidic acid | ? | |
2.3.1.51 | acyl-CoA + 1-acyl-sn-glycerol 3-phosphate | involved in phospholipid biosynthesis | Rattus norvegicus | CoA + 1,2-diacyl-sn-glycerol 3-phosphate | - |
? | |
2.3.1.51 | palmitoyl-CoA + 1-acyl-sn-glycerol 3-phosphate | - |
Rattus norvegicus | CoA + 1-acyl-2-palmitoyl-sn-glycerol 3-phosphate | - |
? |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
2.3.1.42 | 5.5 | - |
membrane-bound peroxisomal enzyme | Rattus norvegicus |
2.3.1.42 | 5.5 | - |
membrane-bound peroxisomal enzyme | Oryctolagus cuniculus |
2.3.1.42 | 7.5 | - |
microsomal enzyme | Rattus norvegicus |
2.3.1.42 | 7.5 | - |
microsomal enzyme | Oryctolagus cuniculus |