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Literature summary extracted from

  • Saito, K.; Shinohara, A.; Kamataki, T.; Kato, R.
    A new assay for N-hydroxyarylamine O-acetyltransferase: reduction of N-hydroxyarylamines through N-acetoxyarylamines (1986), Anal. Biochem., 152, 226-231.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.3.1.118 dithiothreitol
-
 Salmonella enterica subsp. enterica serovar Typhimurium

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.3.1.118 1-Nitro-2-naphthol
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.3.1.118 Pentachlorophenol
-
 Salmonella enterica subsp. enterica serovar Typhimurium
2.3.1.118 thiolactomycin
-
 Rattus norvegicus
2.3.1.118 thiolactomycin
-
 Salmonella enterica subsp. enterica serovar Typhimurium

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.3.1.118 0.0033
-
 acetyl-CoA fluorometric method Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number Organism UniProt Comment Textmining
2.3.1.118 Rattus norvegicus
-
 Sprague-Dawley strain
-
2.3.1.118 Rattus norvegicus Sprague-Dawley
-
 Sprague-Dawley strain
-
2.3.1.118 Salmonella enterica subsp. enterica serovar Typhimurium
-
-
-
2.3.1.118 Salmonella enterica subsp. enterica serovar Typhimurium TA98
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.3.1.118 partial, using DEAE Cellulose and Sephacryl S-200 chromatography Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.3.1.118 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.3.1.118 acetyl-CoA + 2-hydroxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 Salmonella enterica subsp. enterica serovar Typhimurium CoA + N-acetoxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 ?
2.3.1.118 acetyl-CoA + 2-hydroxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 Rattus norvegicus CoA + N-acetoxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 ?
2.3.1.118 acetyl-CoA + 2-hydroxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 Rattus norvegicus Sprague-Dawley CoA + N-acetoxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 ?
2.3.1.118 acetyl-CoA + 2-hydroxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 Salmonella enterica subsp. enterica serovar Typhimurium TA98 CoA + N-acetoxy-amino-6-methyldipyrido[1,2-a: 3',2'-d]imidazole
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.3.1.118 37
-
 assay at Salmonella enterica subsp. enterica serovar Typhimurium

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.3.1.118 7
-
 assay at Salmonella enterica subsp. enterica serovar Typhimurium