Literature summary extracted from

Fritsche, E.; Bergner, A.; Humm, A.; Piepersberg, W.; Huber, R.
Crystal Structure of L-Arginine:Inosamine-Phosphate Amidinotransferase StrB1 from Streptomyces griseus: An Enzyme Involved in Streptomycin Biosynthesis (1998), Biochemistry, 37, 17664-17672.

Cloned(Commentary)

EC Number	Cloned (Comment)	Organism
2.1.4.2	strain strB1, cloned as N-terminal hexa-histidine fusion protein	Streptomyces griseus

Crystallization (Commentary)

EC Number	Crystallization (Comment)	Organism
2.1.4.2	tetragonal-bipyramidal shaped crystals, belonging to the tetragonal space group P4(3), a = b = 121.3 A, c = 63.74 A	Streptomyces griseus

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces griseus	-	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces galbus	-	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces glaucescens strB1	-	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces glaucescens strB2	-	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces griseus strB1	-	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces griseus	biosynthesis of streptomycin	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	Streptomyces galbus strB1	-	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.4.2	Streptomyces galbus	-	strB1	-
2.1.4.2	Streptomyces galbus strB1	-	strB1	-
2.1.4.2	Streptomyces glaucescens strB1	Q54258	strB1, genebank acc. No.	-
2.1.4.2	Streptomyces glaucescens strB2	Q54264	strB2, genebank acc. No.	-
2.1.4.2	Streptomyces griseus	-	-	-
2.1.4.2	Streptomyces griseus	P08078	EMBL accession number	-
2.1.4.2	Streptomyces griseus	P08078	strB1, genbank seq.acc. number	-
2.1.4.2	Streptomyces griseus strB1	P08078	EMBL accession number	-

Purification (Commentary)

EC Number	Purification (Comment)	Organism
2.1.4.2	recombinant enzyme	Streptomyces griseus

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
2.1.4.2	mycelium	-	Streptomyces galbus	-
2.1.4.2	mycelium	-	Streptomyces griseus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.
2.1.4.2	2-deoxystreptidine 6-phosphate + scyllo-inosaminephosphate	-	Streptomyces griseus	?	-	?
2.1.4.2	arginine + 2-amino-2-deoxy-neo-inositol 5-phosphate	-	Streptomyces griseus	?	-	?
2.1.4.2	arginine + 3-amino-3-deoxy-scyllo-inosamine 4-phosphate	-	Streptomyces griseus	?	-	?
2.1.4.2	arginine + canaline	-	Streptomyces griseus	?	-	?
2.1.4.2	arginine + hydroxylamine	-	Streptomyces griseus	ornithine + hydroxyguanidine	-	?
2.1.4.2	arginine + N-amidinostreptamine 6-phosphate	-	Streptomyces griseus	?	-	?
2.1.4.2	arginine + ornithine	-	Streptomyces griseus	?	-	?
2.1.4.2	arginine + scyllo-inosamine 4-phosphate	-	Streptomyces griseus	ornithine + N-amidino-scyllo-inosamine-4-phosphate	-	?
2.1.4.2	arginine + scyllo-inosamine 4-phosphate	-	Streptomyces griseus	?	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	-	Streptomyces griseus	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	-	Streptomyces galbus	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	-	Streptomyces glaucescens strB1	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	-	Streptomyces glaucescens strB2	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	-	Streptomyces griseus strB1	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	biosynthesis of streptomycin	Streptomyces griseus	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol 4-phosphate	-	Streptomyces galbus strB1	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate	-	Streptomyces griseus	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate	-	Streptomyces galbus	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate	-	Streptomyces glaucescens strB1	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate	-	Streptomyces glaucescens strB2	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate	-	Streptomyces griseus strB1	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-arginine + 1-amino-1-deoxy-scyllo-inositol-4-phosphate	-	Streptomyces galbus strB1	L-ornithine + 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate	-	?
2.1.4.2	L-canavanine + L-ornithine	-	Streptomyces griseus	L-canaline + L-arginine	-	r
2.1.4.2	N-amidino-scyllo-inosamine 4-phosphate + scyllo-inosaminephosphate	weak amidino donor	Streptomyces griseus	?	-	?
2.1.4.2	streptidine 6-phosphate + scyllo-inosaminephosphate	-	Streptomyces griseus	?	-	?
2.1.4.2	streptidine phosphate + glycylglycine	-	Streptomyces griseus	?	-	?