Literature summary extracted from
Tricot, C.; Villeret, V.; Sainz, G.; Dideberg, O.; Stalon, V.
Allosteric regulation in Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase revisited: association of concerted homotropic cooperative interactions and local heterotropic effects (1998), J. Mol. Biol., 283, 695-704.
Activating Compound
EC Number |
Activating Compound |
Comment |
Organism |
Structure |
---|
2.1.3.3 |
AMP |
- |
Pseudomonas aeruginosa |
|
2.1.3.3 |
arsenate |
potent activator in the concentration range of 0-10 mM |
Pseudomonas aeruginosa |
|
2.1.3.3 |
phosphate |
potent activator in the concentration range of 0-10 mM |
Pseudomonas aeruginosa |
|
Protein Variants
EC Number |
Protein Variants |
Comment |
Organism |
---|
2.1.3.3 |
E105G |
no cooperativity towards carbamoyl phosphate, follows Michaelis-Menten kinetics |
Pseudomonas aeruginosa |
Inhibitors
EC Number |
Inhibitors |
Comment |
Organism |
Structure |
---|
2.1.3.3 |
spermidine |
E105G mutant enzyme, competitive vs. carbamoylphosphate |
Pseudomonas aeruginosa |
|
Organism
EC Number |
Organism |
UniProt |
Comment |
Textmining |
---|
2.1.3.3 |
Pseudomonas aeruginosa |
- |
catabolic ornithine carbamoyltransferase |
- |