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Literature summary extracted from

  • Maloy, W.L.; Bowien, B.U.; Zwolinski, G.K.; Kumar, K.G.; Wood, H.G.; Ericsson, L.H.; Walsh, K.A.
    Amino acid sequence of the biotinyl subunit from transcarboxylase (1979), J. Biol. Chem., 254, 11615-11622.
    View publication on PubMed

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.1.3.1 Co2+ requirement Propionibacterium freudenreichii subsp. shermanii

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.3.1 additional information
-
 two active forms of enzyme: 18S and 26S Propionibacterium freudenreichii subsp. shermanii
2.1.3.1 120000
-
 the 26S holoenzyme consists of a hexameric central 12S subunit, 360000 Da and six peripheral dimeric 5S subunits, 6 * 120000 Da each of which is linked to the central subunit by 2 biotinyl 1.3S subunits, 12 * MW 12000 Propionibacterium freudenreichii subsp. shermanii

Organism

EC Number Organism UniProt Comment Textmining
2.1.3.1 Propionibacterium freudenreichii subsp. shermanii
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.3.1
-
 Propionibacterium freudenreichii subsp. shermanii

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.3.1 propionyl-CoA + oxaloacetate
-
 Propionibacterium freudenreichii subsp. shermanii (S)-methylmalonyl-CoA + pyruvate
-
 r

Subunits

EC Number Subunits Comment Organism
2.1.3.1 More amino acid sequence of biotinyl subunit Propionibacterium freudenreichii subsp. shermanii
2.1.3.1 More the 26S holoenzyme consists of a hexameric central 12S subunit, 360000 Da and six peripheral dimeric 5S subunits, 6 * 120000 Da each of which is linked to the central subunit by 2 biotinyl 1.3S subunits, 12 * MW 12000 Propionibacterium freudenreichii subsp. shermanii

pH Stability

EC Number pH Stability pH Stability Maximum Comment Organism
2.1.3.1 5.5
-
 26S-form stable Propionibacterium freudenreichii subsp. shermanii
2.1.3.1 6.8
-
 18S form stable Propionibacterium freudenreichii subsp. shermanii

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.3.1 biotin requirement Propionibacterium freudenreichii subsp. shermanii