BRENDA - Enzyme Database

enzymatic study of the late stages of protoberberine alkaloid biosynthesis

Beecher, C.W.W.; Kelleher, W.J.; Tetrahedron Lett. 25, 4595-4598 (1984)
No PubMed abstract available

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.89
S-adenosyl-L-methionine + tetrahydrocolumbamine
Berberis aggregata
enzyme is involved in the biosynthesis of berberine alkaloids
S-adenosyl-L-homocysteine + tetrahydropalmatine
-
Berberis aggregata
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
2.1.1.89
Berberis aggregata
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.89
callus
-
Berberis aggregata
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.89
S-adenosyl-L-methionine + tetrahydrocolumbamine
no activity with tetrahydrojatrorhizine, tetrahydropalmatrubine, columbamine, jatrorrhizine and palmatrubine
485659
Berberis aggregata
S-adenosyl-L-homocysteine + tetrahydropalmatine
-
485659
Berberis aggregata
?
2.1.1.89
S-adenosyl-L-methionine + tetrahydrocolumbamine
enzyme is involved in the biosynthesis of berberine alkaloids
485659
Berberis aggregata
S-adenosyl-L-homocysteine + tetrahydropalmatine
-
485659
Berberis aggregata
?
Temperature Optimum [°C]
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.1.1.89
30
-
assay at
Berberis aggregata
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
2.1.1.89
S-adenosyl-L-methionine + tetrahydrocolumbamine
Berberis aggregata
enzyme is involved in the biosynthesis of berberine alkaloids
S-adenosyl-L-homocysteine + tetrahydropalmatine
-
Berberis aggregata
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
2.1.1.89
callus
-
Berberis aggregata
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
2.1.1.89
S-adenosyl-L-methionine + tetrahydrocolumbamine
no activity with tetrahydrojatrorhizine, tetrahydropalmatrubine, columbamine, jatrorrhizine and palmatrubine
485659
Berberis aggregata
S-adenosyl-L-homocysteine + tetrahydropalmatine
-
485659
Berberis aggregata
?
2.1.1.89
S-adenosyl-L-methionine + tetrahydrocolumbamine
enzyme is involved in the biosynthesis of berberine alkaloids
485659
Berberis aggregata
S-adenosyl-L-homocysteine + tetrahydropalmatine
-
485659
Berberis aggregata
?
Temperature Optimum [°C] (protein specific)
EC Number
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
2.1.1.89
30
-
assay at
Berberis aggregata