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Literature summary extracted from

  • Beecher, C.W.W.; Kelleher, W.J.
    enzymatic study of the late stages of protoberberine alkaloid biosynthesis (1984), Tetrahedron Lett., 25, 4595-4598.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.89 S-adenosyl-L-methionine + tetrahydrocolumbamine Berberis aggregata enzyme is involved in the biosynthesis of berberine alkaloids S-adenosyl-L-homocysteine + tetrahydropalmatine
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.89 Berberis aggregata
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.1.1.89 callus
-
 Berberis aggregata
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.89 S-adenosyl-L-methionine + tetrahydrocolumbamine no activity with tetrahydrojatrorhizine, tetrahydropalmatrubine, columbamine, jatrorrhizine and palmatrubine Berberis aggregata S-adenosyl-L-homocysteine + tetrahydropalmatine
-
 ?
2.1.1.89 S-adenosyl-L-methionine + tetrahydrocolumbamine enzyme is involved in the biosynthesis of berberine alkaloids Berberis aggregata S-adenosyl-L-homocysteine + tetrahydropalmatine
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.1.1.89 30
-
 assay at Berberis aggregata