Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Pollock, R.J.; Hersh, L.B.
    N-Methylglutamate synthetase. The use of flavin mononucleotide in oxidative catalysis (1973), J. Biol. Chem., 248, 6724-6733.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.1.21 ammonia competitive with respect to methylamine Pseudomonas sp.
2.1.1.21 N-methylglutamate weak product inhibition Pseudomonas sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.1.1.21 methylamine + L-glutamate Pseudomonas sp.
-
 NH3 + N-methyl-L-glutamate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
2.1.1.21 Pseudomonas sp.
-
 strain ATCC 23819
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.1.21 methylamine + L-glutamate
-
 Pseudomonas sp. NH3 + N-methyl-L-glutamate
-
 r
2.1.1.21 methylamine + L-glutamate Ping Pong Bi Bi kinetic pattern, glutaryl enzyme intermediate, no inversion during reaction Pseudomonas sp. NH3 + N-methyl-L-glutamate
-
 r

Cofactor

EC Number Cofactor Comment Organism Structure
2.1.1.21 FMN
-
 Pseudomonas sp.