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Literature summary extracted from

  • Percy, A.K.; Moore, J.F.; Carson, M.A.; Waechter, C.J.
    Characterization of brain phosphatidylserine decarboxylase: localization in the mitochondrial inner membrane (1983), Arch. Biochem. Biophys., 223, 484-494.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
4.1.1.65 Cutsum maximal activity in presence of 0.1% cutsum Bos taurus
4.1.1.65 sodium taurocholate maximal activity in presence of 0.1% sodium taurocholate Bos taurus

Inhibitors

EC Number Inhibitors Comment Organism Structure
4.1.1.65 hydroxylamine
-
 Bos taurus
4.1.1.65 hydroxylamine
-
 Rattus norvegicus
4.1.1.65 p-hydroxymercuribenzoate
-
 Bos taurus

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
4.1.1.65 2.4
-
 phosphatidylserine
-
 Bos taurus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.1.65 membrane
-
 Rattus norvegicus 16020
-
4.1.1.65 mitochondrial inner membrane membrane Rattus norvegicus 5743
-
4.1.1.65 mitochondrial inner membrane inner membrane Bos taurus 5743
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
4.1.1.65 additional information no requirement for divalent metal ions Bos taurus

Organism

EC Number Organism UniProt Comment Textmining
4.1.1.65 Bos taurus
-
 calf
-
4.1.1.65 Rattus norvegicus
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
4.1.1.65 brain
-
 Rattus norvegicus
-
4.1.1.65 brain
-
 Bos taurus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.1.65 Phosphatidyl-L-serine
-
 Rattus norvegicus Phosphatidylethanolamine + CO2
-
 ?
4.1.1.65 Phosphatidyl-L-serine
-
 Bos taurus Phosphatidylethanolamine + CO2
-
 ?

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
4.1.1.65 37 40
-
 Bos taurus

Temperature Range [°C]

EC Number Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
4.1.1.65 35 50 35°C: about 60% of maximal activity, 50°C: about 25% of maximal activity Bos taurus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
4.1.1.65 7
-
-
 Bos taurus

pH Range

EC Number pH Minimum pH Maximum Comment Organism
4.1.1.65 6 8.5 pH 6.0: about 35% of maximal activity, pH 8.5: about 50% of maximal activity Bos taurus